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Biologics/Biomaterials

Showing 49–64 of 79 results

Sports Medicine and Tendon Reinforcement Market Analysis | United States | 2017-2023 | MedCore

The tendon reinforcement market constitutes a significant portion of the U.S. sports medicine market. Tendons have been traditionally repaired with the surgical use of suture anchoring technology to directly rejoin a torn tendon. One issue with traditional tendon repair is the incidence of re-tearing previously operated injuries. This predominantly occurs following procedures involving the repair of the shoulder’s rotator cuff tendons and the ankle’s Achilles tendon.

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Skin Repair Market Analysis | United States | 2017-2023 | MedCore

Soft tissue repair devices used for skin repair are unique in the sense that they are laid directly over the skin. This separates skin repair devices from soft tissue repair devices used for other indications that require complex surgical implantation. This report will focus on a specific class of skin repair wound dressings called interactive wound dressings. Interactive dressings are designed to work synergistically with the body’s healing process, similarly to other soft tissue repair devices. Interactive dressings become involved with the body’s physiology and mimic substances in the body’s wound healing pathways that are lacking in situations with chronic wounds or in burn patients. The interactive dressings market includes skin substitutes and collagen dressings.

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Dental Soft Tissue Regeneration Market Analysis | United States | 2020-2026 | MedCore

Dental soft tissue regeneration devices are used to facilitate the regeneration of soft tissue, either in response to soft tissue recession or during a dental implant procedure. Applications for the devices include soft tissue augmentation around dental implants, root coverage, gingival augmentation and soft tissue ridge augmentation. The two main classes of dental soft tissue regeneration products are allografts (human tissue-derived) and xenografts (non-human animal tissue-derived). This market does not include alloplasts, as these products fall into the barrier membrane category.

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Breast Reconstruction Market Analysis | United States | 2020-2026 | MedCore

Breast reconstruction following mastectomy for treatment of cancer is becoming increasingly popular in the United States. Breast reconstruction is a plastic surgery procedure in which the shape of the breast is rebuilt. The number of these reconstructive procedures represents less than 30% of plastic surgery breast augmentation procedures. Breast reconstruction is typically performed after mastectomy, although not all mastectomy patients elect to have reconstructive surgery. Elderly patients are not only less likely to opt for breast reconstruction surgery, but are less likely to proceed with a mastectomy following breast cancer diagnosis. The incidence of breast cancer has been increasing in women under the age of 40, and this population is much more likely not only to proceed with mastectomy, but to follow up with a breast reconstruction procedure. Over 130,000 mastectomies were performed in the U.S. in 2016, and of these, over 70% of patients elected for breast reconstruction surgery. This percentage was significantly higher in the U.S. compared with other countries. Therefore, in the United States, the number of breast reconstruction procedures is highly correlated with the number of mastectomies performed. The Women’s Health and Cancer Rights Act (WHCRA), established in 1998, ensures full reimbursement for most procedures done on women with breast cancer who elect to have their breasts rebuilt following mastectomy. The procedure is extremely involved and is done in an inpatient setting. Breast reconstructions have started to be conducted immediately after the mastectomy procedure to reduce recovery time.

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Dural Repair Market Analysis | United States | 2020-2026 | MedCore

The dura mater is a tough, fibrous membrane that surrounds and protects the tissues of the brain and spinal cord. Dural repair is primarily performed for head and spinal injuries where a laceration has occurred to the dura, and for neurosurgical procedures in which the dura is required to be opened or removed to gain access to the bones or delicate tissues within. In both cases, effective dural closure is imperative to prevent cerebrospinal fluid (CSF) leakage and permit proper and expeditious wound healing. Since CSF leaks often result in extra time and cost associated with patient care, dural repair performed with appropriate devices is integral for significant savings for surgeons and patients.

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Dental Bone Grafting Procedure Volume & COVID19 Impact Analysis | United States | 2021-2027 | MedPro | Includes: Dental Implant & Periodontal Procedures Performed with Bone Grafts

The full report suite on the U.S. market for dental bone graft substitutes (DBGS) and other biomaterials includes dental bone graft substitutes, dental growth factors and dental barrier membranes.

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Dental Barrier Membranes Market Size, Share & COVID19 Impact Analysis | United States | 2021-2027 | MedCore | Segmented by: Type (Resorbable, Non-Resorbable) & Material (Xenografts, Allografts, Synthetics)

Barrier membranes are a critical component to regeneration therapy and are aimed at restoring the form and function of the mouth. Commercially available on the market, barrier membranes function in dental surgeries to help retain bone grafting materials, to exclude epithelium and connective tissue from entering into sites of desired bone and ligament regeneration, or for the combination of these reasons. Whether restoring lost bone around teeth or implants, or in larger areas of the jaws affected by trauma or disease, too often there is inadequate gingival tissue to cover the membranes, leading to membrane exposure, extensive membrane contamination and procedural failure, which is unacceptable.

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Dental Growth Factor Market Size, Share & COVID19 Impact Analysis | United States | 2021-2027 | MedCore | Segmented by: Product (Emdogain®, GEM 21S®, Infuse™, Osteocel®)

Dental growth factor and tissue engineering products is a broad category that encompasses products used for facilitating and enhancing bone regeneration. This includes growth factors and enamel matrix protein solutions. Platelet rich plasma (PRP) is also used for these purposes, but will not be considered within this report.

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Orthopedic Biomaterials Procedure Volume Analysis | Europe | 2019-2025 | MedPro

The full report suite on the U.S.European market for orthopedic biomaterials includes bone graft substitutes, which is represented by allografts, demineralized bone matrix and synthetic bone graft market. The report also includes hyaluronic acid viscosupplementation, orthopedic growth factors, orthopedic cell therapy, orthopedic cartilage repair and spinal machined bone allograft markets.

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Cartilage Repair Market Analysis | Europe | 2017-2023 | MedCore

Articular cartilage is a connective tissue that lines the ends of bones in joints. It provides shock absorption within the joint and prevents abrasion from occurring to the articular surfaces of bone. Cartilage, in its various forms, is found in intervertebral discs, as the articular lining for joint surfaces and in the meniscal pads of the knees. All types of this tissue are poorly vascularized and, as proper healing requires adequate blood flow, cartilage is one of the slowest healing tissues of the body. Osteoarthritis is cumulative trauma that eventually wears away at cartilaginous surfaces, exposing the underlying bone to additional wear. There are few alternatives to osteobiologic cartilage repair. Damage to cartilage is difficult to treat because the tissue lacks blood supply and has limited capacity for self repair.

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Bone Graft Substitutes Market Analysis | Europe | 2019-2025 | MedCore

Bones are biologically active tissues that allow for movement, provide protection for the body’s other organs and serve as a production center for red and white blood cells. When bones are diseased or damaged, bone grafts and bone graft substitutes are used for bridging the resulting void or for providing the support that has been lost. The transplanted (or implanted) material provides a scaffold on which the body can generate new bone tissue, thereby repairing the skeletal system. The most common usage of such materials is for dental implants to replace missing teeth. Within the orthopedic field, however, spinal fusion surgeries are the largest driver of bone graft and bone graft substitute usage. Direct competition for bone graft substitutes comes from bone morphogenetic proteins which, although more expensive, are more effective at stimulating bone growth. Another source of competition is the rise of the motion preservation market for spinal surgery.

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Bone Morphogenic Protein Growth Factor Therapy Market Analysis | Europe | 2017-2023 | MedCore

Bone morphogenetic proteins (BMPs) are growth factors that induce the formation of bone after a fracture. In nature, these proteins have a critical role during embryonic development in the formation of the skeleton. There are twenty different BMPs that have been discovered thus far, of which only two, BMP-2 and BMP-7, have been commercialized as bone graft substitutes for use in specific orthopedic procedures. The commercial versions of these products are produced by recombinant genetic engineering, which results in a recombinant human protein. The recombinant human BMP-2 (rhBMP-2) is marketed as a commercial product by Medtronic, Inc. and is called Infuse® (InductOS® in Europe), while BMP-7 has been commercialized by Stryker Inc. and is sold to Olympus under the name of OP-1®. Both molecules mediate the process of osteoblast differentiation. BMP-2 is capable of stimulating immature mesenchymal cells to form into bone, while BMP-7 has been shown to be capable of stimulating cartilage growth.

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Orthopedic Bone Graft Substitutes Market Analysis | United States | 2019-2025 | MedCore

Bone is a biologically active tissue and will regenerate whenever possible; however, there are instances where the damage is significant enough to warrant a scaffold to help rejoin the fissure or cavity. Bone grafting is a surgical procedure in which damaged bone is replaced with autograft tissue, allograft tissue or a bone graft substitute, which can be either synthetic or metal.
During an autograft procedure, tissue is harvested from the patient’s iliac crest, or possibly the distal femur or proximal tibia, and placed at the injury site. An allograft procedure uses donated cadaveric tissue. A grafting procedure using a bone graft substitute replaces human tissue with a synthetic or metal material. For the purposes of this report, metal replacement materials will be excluded, as they are not considered biomaterials.

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Cellular Allografts Market Analysis | United States | 2019-2025 | MedCore

Cellular allografts consist of allograft bone combined with adipose derived mesenchymal stem cells; or may refer to HCT/P (Human Cells, Tissues, and Cellular and Tissue-based Product) comprised of viable cells within a cortical cancellous bone matrix. The viable cell bone matrix (VCBM) is a cryopreserved cancellous bone combined with demineralized cortical bone matrix. Their key characteristic in regards to bone repair is that they provide osteogenic properties.

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Orthopedic Cartilage Repair Market Analysis | United States | 2019-2025 | MedCore

Cartilage is a connective tissue that lines the ends of bones. It provides shock absorption within the joint and prevents abrasion from occurring to the articular surfaces of bone. Cartilage, in its various forms, is found in intervertebral discs, as the articular lining for joint surfaces and in the meniscal pads of the knees. All types of cartilage are poorly vascularized and, as proper healing requires adequate blood flow, are some of the slowest healing tissues of the body.
Osteoarthritis is cumulative trauma that eventually wears away at cartilaginous surfaces, exposing the underlying bone to additional wear. There are few alternatives for osteobiologic cartilage repair. Damage to cartilage is difficult to treat because the tissue lacks blood supply and has limited capacity for self-repair.

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Orthopedic Cell Therapy Market Analysis | United States | 2019-2025 | MedCore

The scope of the orthopedic cell therapy market in this report covers platelet-rich plasma and concentrated bone marrow aspirate.
The platelet and bone marrow concentration market consists of centrifuge equipment that separates and concentrates platelets and cells based on their various densities. The majority of companies participating in this market provide the centrifuges on loan and sell only the disposable components, such as the spin buckets. Typically, one bucket is required per procedure.

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