Orthobiologics Market Analysis, Size, Trends | Japan | 2020-2026 | MedSuite

  • Year: 2020
  • Scope: 2016-2026
  • Region: Japan
  • Pages: 187
  • Published Date: 02/14/2020
  • Type: MedSuite

In 2020, the Japanese orthobiologics market size was valued at $426.9 million, with over 221,000 bone grafting procedures performed every year. The market size is expected to fluctuate over the forecast period with a -0.4% compound annual growth rate (CAGR).

Throughout this medical market research, we analyzed 16 orthobiologics companies across Japan and used our comprehensive methodology to understand the market sizes, unit sales, company market shares, and to create accurate forecasts.

While this MedSuite report contains all of the Japanese Orthopedic Biomaterials market data and analysis, each of the market segments is also available as stand-alone MedCore reports. This allows you to get access to only the market research that you need.


  • Unit Sales, Average Selling Prices, Market Value & Growth Trends
  • Orthobiologics Procedure Volumes
  • Market Forecasts Until 2026, and Historical Data to 2016
  • Competitive Analysis with Market Shares for Each Segment
  • Market Drivers & Limiters for Each Orthopedic Biomaterials Device market
  • Recent Mergers & Acquisitions
  • Disease Overviews and Demographic Information
  • Company Profiles, Product Portfolios and SWOT for Top Competitors

Market Value and Industry Trends

A lack of product differentiation across similar injection cycle products has led to commoditization, which has stifled innovation and the further development of new products. The prices of HA viscosupplementation products in Japan have drastically decreased since their introduction and are among the lowest in the world.

Japan Orthobiologics Market Size by Segment, 2016-2026

Surgical procedures that require the use of orthopedic biomaterials are generally associated with diseases and indications that become more prevalent in the population with an increase in age, such as osteoarthritis of the spine and knee. In 2019, approximately 29% of the Japanese population were aged 65 and over; this proportion is projected to grow steadily over the forecast period, as further cohorts of baby boomers turn 65. Growth of this population is expected to stimulate growth across all segments of the orthopedic biomaterials market.

In August 2018, Medtronic received PMDA approval for its Grafton® DBM allograft product, which is the first DBM allograft to be approved in Japan. Grafton® was commercially launched in February 2019. The growth of this product will be primarily driven by spine procedures and other orthopedic procedures that it is indicated for.

Competitive Analysis

India Orthopedic Biomaterials Market Leaders

By 2020, the leading competitor in the Japanese orthopedic biomaterials market was Seikagaku, which was attributed to its dominant position in the HA viscosupplementation market. The company’s portfolio includes the five-injection ARTZ® product line.

Chugai was the second-leading competitor in the Japanese market, which was attributed to its second-leading position in the HA viscosupplementation market. The company’s portfolio includes the Suvenyl® product line.

Segments Covered

Click on each title to view more detailed market segmentation.

  • Procedure Volumes for Orthopedic Biomaterials DevicesMedPro – The complete procedural analysis for each segment of the Japanese Orthopedic Biomaterials market.
  • Orthopedic Bone Graft Substitute Market – MedCore – This market is further segmented by Indication, including Spine, Trauma, Large Joint Reconstruction, Craniomaxillofacial, and Oncology.
  • Hyaluronic Acid Viscosupplementation Market – MedCore – This market is categorized by Treatment Type, including Three-Injection and Five-Injection.

Detailed Market Segmentation


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TABLE OF CONTENTS ILIST OF FIGURES VIILIST OF CHARTS XIIEXECUTIVE SUMMARY 1JAPANESE ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW 1COMPETITIVE ANALYSIS 3MARKET TRENDS 5MARKET DEVELOPMENTS 6PROCEDURE NUMBERS 7MARKETS INCLUDED 8VERSION HISTORY 8RESEARCH METHODOLOGY 9Step 1: Project Initiation & Team Selection 9Step 2: Prepare Data Systems and Perform Secondary Research 12Step 3: Preparation for Interviews & Questionnaire Design 14Step 4: Performing Primary Research 15Step 5: Research Analysis: Establishing Baseline Estimates 17Step 6: Market Forecast and Analysis 18Step 7: Identify Strategic Opportunities 20Step 8: Final Review and Market Release 21Step 9: Customer Feedback and Market Monitoring 22


2.1 INTRODUCTION 232.2 PRODUCT PORTFOLIOS 232.2.1 Bone Graft Substitutes 242.2.2 Growth Factors 302.2.2.1 Other Products 332.2.3 Hyaluronic Acid Viscosupplementation (HAV) 352.3 REGULATORY ISSUES AND RECALLS 382.3.1 Bone Graft Substitutes 382.3.1.1 Allografts 382. MTF 382.3.1.2 DBM 382. AlloSource 382. SeaSpine 392. RTI Surgical 392.3.1.3 Synthetics 392. Abyrx 392. Zimmer Biomet 402.3.2 Growth Factors 402. Medtronic 402.3.3 Hyaluronic Acid Viscosupplementation 412.3.3.1 Three-injection 412. Ferring Pharmaceuticals 412.4 CLINICAL TRIALS 422.4.1 Bone Graft Substitutes 422.4.1.1 Allografts 422. Providence Medical Technology 422. The University of Texas Health Science 422. University of Winchester 432.4.1.2 BDM 432. K2M 432. Zimmer Biomet 442.4.1.3 Synthetics 442. Baxter 442. Bonesupport 452. DePuy Synthes 452. NuVasive 472. RTI surgical 472. Sunstar GUIDOR 482.4.1.4 Other materials and comparison 492. Seoul National University Hospital. 492. Sewon Cellontech 492. SurgaColl Technologies Limited 502. University of Colorado 502. University of Padova 512.4.2 Growth Factors 512. Bioventus 512. Cerapedics 522. CGBio 522. Isto 532. Medtronic 532. NuVasive 552. Wright 552. Others 562.4.3 Hyaluronic Acid Viscosupplementation 572. Anika Therapeutics 572. Bioventus 582. Cairo University 592. Ferring Pharmaceuticals 592. Federal University of Minas Gerais 602. Fidia Pharma USA Inc. 602. Istituto Ortopedico Rizzoli 612. University Hospital 612. Universidade Nova de Lisboa 62


3.1 INTRODUCTION 633.1.1 Bone Graft Substitutes 633.1.2 Growth Factors 633.1.3 Hyaluronic Acid (HA) Viscosupplementation 643.2 CURRENCY EXCHANGE RATE 653.3 MARKET OVERVIEW AND TREND ANALYSIS 663.4 DRIVERS AND LIMITERS 733.4.1 Market Drivers 733.4.2 Market Limiters 733.5 COMPETITIVE MARKET SHARE ANALYSIS 753.6 MERGERS AND ACQUISITIONS 793.7 COMPANY PROFILES 813.7.1 Anika Therapeutics 813.7.2 Bioventus 823.7.3 DePuy Synthes 833.7.4 Ferring Pharmaceuticals 843.7.5 Fidia Pharmaceuticals 853.7.6 Genzyme (Sanofi Group) 863.7.7 Harvest Technologies (Terumo BCT) 873.7.8 Integra LifeSciences 883.7.9 Medtronic 893.7.10 Musculoskeletal Transplant Foundation (MTF) 913.7.11 NuVasive 923.7.12 Orthofix 933.7.13 RTI Surgical 943.7.14 Stryker 953.7.15 Vericel Corporation (formerly Aastrom Bioscience) 963.7.16 Zimmer Biomet 973.8 SWOT ANALYSIS 993.8.1 Anika Therapeutics 993.8.2 Bioventus 1013.8.3 DePuy Synthes 1033.8.4 Ferring Pharmaceuticals 1043.8.5 Fidia Pharmaceuticals 1053.8.7 Harvest Technologies (Terumo BCT) 1073.8.8 Integra LifeSciences 1083.8.9 Medtronic 1093.8.10 Musculoskeletal Transplant Foundation (MTF) 1103.8.11 NuVasive 1113.8.12 Orthofix 1123.8.14 Stryker 1143.8.15 Vericel Corporation (formerly Aastrom Bioscience) 1153.8.16 Zimmer Biomet 116


4.1 INTRODUCTION 1184.2 PROCEDURES 1194.2.1 Orthopedic Biomaterial Procedures by Segment 1194.2.2 Orthopedic Bone Grafting Procedures 1214.2.2.1 Units per Procedure by Indication 1234.2.2.2 Autograft Orthopedic Bone Grafting Procedures by Indication 1244.2.2.3 Synthetic Orthopedic Bone Grafting Procedures by Indication 1274.2.3 Hyaluronic Acid Supplementation Procedures 1304.2.3.1 Hyaluronic Acid Supplementation Procedures by Injection Cycle 130


5.1 INTRODUCTION 1325.2 MARKET ANALYSIS AND FORECAST 1335.2.1.1 Synthetic Bone Graft Substitute Market 1335. Synthetic Bone Graft Substitute Market by Indication 1355.2.1.2 Demineralized Bone Matrix Allograft Bone Graft Substitute Market 1615.3 DRIVERS AND LIMITERS 1625.3.1 Market Drivers 1625.3.2 Market Limiters 1625.4 COMPETITIVE MARKET SHARE ANALYSIS 164


6.1 INTRODUCTION 1676.1.1 Benefits of Viscosupplementation 1686.1.2 Synovial Fluid 1686.2 MARKET OVERVIEW 1696.3 MARKET ANALYSIS AND FORECAST 1756.3.1 Total Hyaluronic Acid Viscosupplementation Market 1756.3.2 Three-Injection Hyaluronic Acid Viscosupplementation Market 1776.3.3 Five-Injection Hyaluronic Acid Viscosupplementation Market 1796.4 DRIVERS AND LIMITERS 1816.4.1 Market Drivers 1816.4.2 Market Limiters 1816.5 COMPETITIVE MARKET SHARE ANALYSIS 183


The Orthobiologics Market Report Suite | Japan | 2020-2026 | MedSuite includes analysis on the following companies currently active in this market:
  • Chugai Pharma
  • CoorsTek
  • DePuy Synthes
  • HOYA Technosurgical
  • Kuraray
  • Maruho
  • Medtronic
  • Meiji Seika Pharma
  • Olympus Terumo Biomaterials
  • Sanofi
  • Seikagaku
  • Stryker
  • Taisho
  • Wright Medical
  • Zimmer Biomet

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