TABLE OF CONTENTS

TABLE OF CONTENTS I

LIST OF FIGURES VIII

LIST OF CHARTS XV

EXECUTIVE SUMMARY 1

INDIAN ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW 1

COMPETITIVE ANALYSIS 3

MARKET TRENDS 5

MARKET DEVELOPMENTS 6

PROCEDURE NUMBERS 7

MARKETS INCLUDED 8

KEY REPORT UPDATES 10

VERSION HISTORY 10

RESEARCH METHODOLOGY 11

Step 1: Project Initiation & Team Selection 11

Step 2: Prepare Data Systems and Perform Secondary Research 14

Step 3: Preparation for Interviews & Questionnaire Design 16

Step 4: Performing Primary Research 17

Step 5: Research Analysis: Establishing Baseline Estimates 19

Step 6: Market Forecast and Analysis 20

Step 7: Identify Strategic Opportunities 22

Step 8: Final Review and Market Release 23

Step 9: Customer Feedback and Market Monitoring 24

PRODUCT ASSESSMENT 25

2.1 INTRODUCTION 25

2.2 PRODUCT PORTFOLIOS 25

2.2.1 Bone Graft Substitutes 26

2.2.2 Growth Factors 32

2.2.2.1 Other Products 35

2.2.3 Hyaluronic Acid Viscosupplementation (HAV) 37

2.3 REGULATORY ISSUES AND RECALLS 40

2.3.1 Bone Graft Substitutes 40

2.3.1.1 Allografts 40

2.3.1.1.1 MTF 40

2.3.1.2 DBM 40

2.3.1.2.1 AlloSource 40

2.3.1.2.2 SeaSpine 41

2.3.1.2.3 RTI Surgical 41

2.3.1.3 Synthetics 41

2.3.1.3.1 Abyrx 41

2.3.1.3.2 Zimmer Biomet 42

2.3.2 Growth Factors 42

2.3.2.1.1 Medtronic 42

2.3.3 Hyaluronic Acid Viscosupplementation 43

2.3.3.1 Three-injection 43

2.3.3.1.1 Ferring Pharmaceuticals 43

2.4 CLINICAL TRIALS 44

2.4.1 Bone Graft Substitutes 44

2.4.1.1 Allografts 44

2.4.1.1.1 Providence Medical Technology 44

2.4.1.1.2 The University of Texas Health Science 44

2.4.1.1.3 University of Winchester 45

2.4.1.2 BDM 45

2.4.1.2.1 K2M 45

2.4.1.2.2 Zimmer Biomet 46

2.4.1.3 Synthetics 46

2.4.1.3.1 Baxter 46

2.4.1.3.2 Bonesupport 47

2.4.1.3.3 DePuy Synthes 47

2.4.1.3.4 NuVasive 49

2.4.1.3.5 RTI surgical 49

2.4.1.3.6 Sunstar GUIDOR 50

2.4.1.4 Other materials and comparison 51

2.4.1.4.1 Seoul National University Hospital. 51

2.4.1.4.2 Sewon Cellontech 51

2.4.1.4.3 SurgaColl Technologies Limited 52

2.4.1.4.4 University of Colorado 52

2.4.1.4.5 University of Padova 53

2.4.2 Growth Factors 53

2.4.2.1.1 Bioventus 53

2.4.2.1.2 Cerapedics 54

2.4.2.1.3 CGBio 54

2.4.2.1.4 Isto 55

2.4.2.1.5 Medtronic 55

2.4.2.1.6 NuVasive 57

2.4.2.1.7 Wright 57

2.4.2.1.8 Others 58

2.4.3 Hyaluronic Acid Viscosupplementation 59

2.4.3.1.1 Anika Therapeutics 59

2.4.3.1.2 Bioventus 60

2.4.3.1.3 Cairo University 61

2.4.3.1.4 Ferring Pharmaceuticals 61

2.4.3.1.5 Federal University of Minas Gerais 62

2.4.3.1.6 Fidia Pharma USA Inc. 62

2.4.3.1.7 Istituto Ortopedico Rizzoli 63

2.4.3.1.8 University Hospital 63

2.4.3.1.9 Universidade Nova de Lisboa 64

INDIAN ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW 65

3.1 INTRODUCTION 65

3.1.1 Bone Graft Substitutes 65

3.1.2 Growth Factors 65

3.1.3 Hyaluronic Acid (HA) Viscosupplementation 66

3.2 CURRENCY EXCHANGE RATE 67

3.3 MARKET OVERVIEW AND TREND ANALYSIS 68

3.4 DRIVERS AND LIMITERS 76

3.4.1 Market Drivers 76

3.4.2 Market Limiters 76

3.5 COMPETITIVE MARKET SHARE ANALYSIS 78

3.6 MERGERS AND ACQUISITIONS 83

3.7 COMPANY PROFILES 85

3.7.1 Anika Therapeutics 85

3.7.2 Bioventus 86

3.7.3 DePuy Synthes 87

3.7.4 Ferring Pharmaceuticals 88

3.7.5 Fidia Pharmaceuticals 89

3.7.6 Genzyme (Sanofi Group) 90

3.7.7 Harvest Technologies (Terumo BCT) 91

3.7.8 Integra LifeSciences 92

3.7.9 Medtronic 93

3.7.10 Musculoskeletal Transplant Foundation (MTF) 95

3.7.11 NuVasive 96

3.7.12 Orthofix 97

3.7.13 RTI Surgical 98

3.7.14 Stryker 99

3.7.15 Vericel Corporation (formerly Aastrom Bioscience) 100

3.7.16 Zimmer Biomet 101

3.8 SWOT ANALYSIS 103

3.8.1 Anika Therapeutics 103

3.8.2 Bioventus 105

3.8.3 DePuy Synthes 107

3.8.4 Ferring Pharmaceuticals 108

3.8.5 Fidia Pharmaceuticals 109

3.8.7 Harvest Technologies (Terumo BCT) 111

3.8.8 Integra LifeSciences 112

3.8.9 Medtronic 113

3.8.10 Musculoskeletal Transplant Foundation (MTF) 114

3.8.11 NuVasive 115

3.8.12 Orthofix 116

3.8.14 Stryker 118

3.8.15 Vericel Corporation (formerly Aastrom Bioscience) 119

3.8.16 Zimmer Biomet 120

PROCEDURE NUMBERS 122

4.1 INTRODUCTION 122

4.1.1 Units per Procedure by Indication 123

4.2 PROCEDURES 124

4.2.1 Orthopedic Biomaterial Procedures by Segment 124

4.2.2 Orthopedic Bone Grafting Procedures 126

4.2.2.1 Orthopedic Bone Grafting Procedures by Material 126

4.2.2.1.1 Autograft Procedures by Indication 128

4.2.2.1.2 Allograft Procedures by Indication 131

4.2.2.1.3 DBM Allograft Procedures by Indication 134

4.2.2.1.4 Synthetic Procedures by Indication 137

4.2.2.2 Orthopedic Bone Grafting Procedures by Indication 140

4.2.3 Orthopedic Growth Factor Procedures 143

4.2.4 Hyaluronic Acid Supplementation Procedures 145

4.2.4.1 Hyaluronic Acid Supplementation Procedures by Injection Cycle 145

ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET 147

5.1 INTRODUCTION 147

5.2 MARKET OVERVIEW 148

5.2.1 Orthopedic Bone Graft Substitute Market by Material 148

5.2.2 Orthopedic Bone Graft Substitute Market by Indication 153

5.3 MARKET ANALYSIS AND FORECAST 159

5.3.1 Total Orthopedic Bone Graft Substitute Market 159

5.3.2 Orthopedic Bone Graft Substitute Market by Material 161

5.3.2.1 Allograft Bone Graft Substitute Market 161

5.3.2.1.1 Allograft Bone Graft Substitute Market by Indication 163

5.3.2.2 Demineralized Bone Matrix Allograft Bone Graft Substitute Market 177

5.3.2.2.1 Demineralized Bone Matrix Allograft Bone Graft Substitute Market by Indication 179

5.3.2.3 Synthetic Bone Graft Substitute Market 193

5.3.2.3.1 Synthetic Bone Graft Substitute Market by Indication 195

5.3.3 Orthopedic Bone Graft Substitute Market by Indication 209

5.3.3.1 Spine Bone Graft Substitute Market 209

5.3.3.2 Cervical Spine Bone Graft Substitute Market 211

5.3.3.3 Thoracolumbar Spine Bone Graft Substitute Market 213

5.3.3.4 Trauma Bone Graft Substitute Market 215

5.3.3.5 Non-Union Trauma Bone Graft Substitute Market 217

5.3.3.6 Fresh Fracture Trauma Bone Graft Substitute Market 219

5.3.3.7 Large Joint Reconstruction Bone Graft Substitute Market 221

5.3.3.8 Hip Reconstruction Bone Graft Substitute Market 223

5.3.3.9 Knee Reconstruction Bone Graft Substitute Market 225

5.3.3.10 Foot Reconstruction Bone Graft Substitute Market 227

5.3.3.11 Craniomaxillofacial Bone Graft Substitute Market 229

5.3.3.12 Oncology Bone Graft Substitute Market 231

5.4 DRIVERS AND LIMITERS 233

5.4.1 Market Drivers 233

5.4.2 Market Limiters 233

5.5 COMPETITIVE MARKET SHARE ANALYSIS 235

ORTHOPEDIC GROWTH FACTOR MARKET 238

6.1 INTRODUCTION 238

6.1.1 BMP-2 (Medtronic) 238

6.2 MARKET ANALYSIS AND FORECAST 240

6.3 DRIVERS AND LIMITERS 242

6.3.1 Market Drivers 242

6.3.2 Market Limiters 242

6.4 COMPETITIVE MARKET SHARE ANALYSIS 244

HYALURONIC ACID VISCOSUPPLEMENTATION MARKET 245

7.1 INTRODUCTION 245

7.1.1 Benefits of Viscosupplementation 246

7.1.2 Synovial Fluid 246

7.2 MARKET OVERVIEW 247

7.3 MARKET ANALYSIS AND FORECAST 253

7.3.1 Total Hyaluronic Acid Viscosupplementation Market 253

7.3.2 Single-Injection Hyaluronic Acid Viscosupplementation Market 255

7.3.3 Three-Injection Hyaluronic Acid Viscosupplementation Market 257

7.3.4 Five-Injection Hyaluronic Acid Viscosupplementation Market 259

7.4 DRIVERS AND LIMITERS 261

7.4.1 Market Drivers 261

7.4.2 Market Limiters 261

7.5 COMPETITIVE MARKET SHARE ANALYSIS 263

ABBREVIATIONS 267

The Orthobiologics Market Report Suite | India | 2020 - 2026 | MedSuite includes analysis on the following companies currently active in this market: • Alkem Laboratories • LG Chem • Anika Therapeutics • Medtronic • Basic Healthcare • MEI • Bharat Biotech • NovaBone • Biocomposites • Sanofi • Bioventus • Sun Pharmaceutical • BONESUPPORT • Surgiwear • DePuy Synthes • Universe Surgical • Dr. Reddy’s Laboratories • Virchow Biotech • Ferring Pharmaceuticals • Wright Medical • Fidia Farmaceutici • Zimmer Biomet • IFGL Bio Ceramics

LIST OF CHARTS

Chart 1 1: Orthopedic Biomaterials Market by Segment, India, 2016 – 2026 2

Chart 1 2: Orthopedic Biomaterials Market Overview, India, 2019 & 2026 2

Chart 3 1: Orthopedic Biomaterials Market by Segment, India, 2016 – 2026 71

Chart 3 2: Orthopedic Biomaterials Market Breakdown, India, 2019 72

Chart 3 3: Orthopedic Biomaterials Market Breakdown, India, 2026 73

Chart 3 4: Growth Rates by Segment, Orthopedic Biomaterials Market, India, 2017 – 2026 75

Chart 3 5: Leading Competitors, Orthopedic Biomaterials Market, India, 2019 82

Chart 4 1: Orthopedic Biomaterials Market by Segment, India, 2016 – 2026 125

Chart 4 2: Orthopedic Bone Grafting Procedures by Material, India, 2016 – 2026 127

Chart 4 3: Autograft Procedures by Indication, India, 2016 – 2026 130

Chart 4 4: Allograft Procedures by Indication, India, 2016 – 2026 133

Chart 4 5: DBM Allograft Procedures by Indication, India, 2016 – 2026 136

Chart 4 6: Synthetic Procedures by Indication, India, 2016 – 2026 139

Chart 4 7: Orthopedic Bone Grafting Procedures by Indication, India, 2016 – 2026 142

Chart 4 8: Orthopedic Growth Factor Procedures, India, 2016 – 2026 144

Chart 4 9: Hyaluronic Acid Viscosupplementation Procedures by Injection Cycle, India, 2016 – 2026 146

Chart 5 1: Orthopedic Bone Graft Substitute Market by Material, India, 2016 – 2026 150

Chart 5 2: Orthopedic Bone Graft Substitute Market Breakdown by Material, India, 2019 151

Chart 5 3: Orthopedic Bone Graft Substitute Market Breakdown by Material, India, 2026 152

Chart 5 4: Orthopedic Bone Graft Substitute Market by Indication, India, 2016 – 2026 156

Chart 5 5: Orthopedic Bone Graft Substitute Market Breakdown by Indication, India, 2019 157

Chart 5 6: Orthopedic Bone Graft Substitute Market Breakdown by Indication, India, 2026 158

Chart 5 7: Total Orthopedic Bone Graft Substitute Market, India, 2016 – 2026 160

Chart 5 8: Allograft Bone Graft Substitute Market, India, 2016 – 2026 162

Chart 5 9: Allograft Bone Graft Substitute Market by Indication, India, 2016 – 2026 164

Chart 5 10: Demineralized Bone Matrix Allograft Bone Graft Substitute Market, India, 2016 – 2026 178

Chart 5 11: Demineralized Bone Matrix Allograft Bone Graft Substitute Market by Indication, India, 2016 – 2026 180

Chart 5 12: Synthetic Bone Graft Substitute Market, India, 2016 – 2026 194

Chart 5 13: Synthetic Bone Graft Substitute Market by Indication, India, 2016 – 2026 196

Chart 5 14: Spine Bone Graft Substitute Market, India, 2016 – 2026 210

Chart 5 15: Cervical Spine Bone Graft Substitute Market, India, 2016 – 2026 212

Chart 5 16: Thoracolumbar Spine Bone Graft Substitute Market, India, 2016 – 2026 214

Chart 5 17: Trauma Bone Graft Substitute Market, India, 2016 – 2026 216

Chart 5 18: Non-Union Trauma Bone Graft Substitute Market, India, 2016 – 2026 218

Chart 5 19: Fresh Fracture Trauma Bone Graft Substitute Market, India, 2016 – 2026 220

Chart 5 20: Large Joint Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 222

Chart 5 21: Hip Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 224

Chart 5 22: Knee Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 226

Chart 5 23: Foot Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 228

Chart 5 24: Craniomaxillofacial Bone Graft Substitute Market, India, 2016 – 2026 230

Chart 5 25: Oncology Bone Graft Substitute Market, India, 2016 – 2026 232

Chart 5 26: Leading Competitors, Orthopedic Bone Graft Substitute Market, India, 2019 237

Chart 6 1: Orthopedic Growth Factor Market, India, 2016 – 2026 241

Chart 7 1: Hyaluronic Acid Viscosupplementation Market by Segment, India, 2016 – 2026 250

Chart 7 2: Hyaluronic Acid Viscosupplementation Market Breakdown, India, 2019 251

Chart 7 3: Hyaluronic Acid Viscosupplementation Market Breakdown, India, 2026 252

Chart 7 4: Total Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 254

Chart 7 5: Single-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 256

Chart 7 6: Three-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 258

Chart 7 7: Five-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 260

Chart 7 8: Leading Competitors, Hyaluronic Acid Viscosupplementation Market, India, 2019 266

LIST OF FIGURES

Figure 1 1: Orthopedic Biomaterials Market Share Ranking by Segment, India, 2019 3

Figure 1 2: Companies Researched in this Report 4

Figure 1 3: Factors Impacting the Orthopedic Biomaterials Market by Segment, India 5

Figure 1 4: Recent Events in the Orthopedic Biomaterials Market, India, 2017 – 2019 6

Figure 1 5: Orthopedic Biomaterials Procedures Covered, India 7

Figure 1 6: Orthopedic Biomaterials Markets Covered (1 of 2) 8

Figure 1 7: Orthopedic Biomaterials Markets Covered (2 of 2) 9

Figure 1 8: Key Report Updates 10

Figure 1 9: Version History 10

Figure 2 1: Bone Graft Substitutes Products by Company (1 of 4) 28

Figure 2 2: Bone Graft Substitutes Products by Company (2 of 4) 29

Figure 2 3: Bone Graft Substitutes Products by Company (3 of 4) 30

Figure 2 4: Bone Graft Substitutes Products by Company (4 of 4) 31

Figure 2 5: Growth Factor Products by Company 36

Figure 2 6: Hyaluronic Acid Viscosupplementation by Products by Company 39

Figure 2 7: Class 2 Device Recall Musculoskeletal Transplant Foundation Allofix Insertion Kit 40

Figure 2 8: Class 2 Device Recall AlloFuse DBM Putty 5cc 40

Figure 2 9: Class 2 Device Recall Accell Evo3c Demineralized Bone Matrix Putty 41

Figure 2 10: Class 2 Device Recall RTI Biologics BioSet IC RT Paste 2 cc 41

Figure 2 11: Class 2 Device Recall Hemostatic Bone Putty 41

Figure 2 12: Class 2 Device Recall Endobon Xenograft Granules 42

Figure 2 13: Class 2 Device Recall Endobon Xenograft Granules 42

Figure 2 14: Class 2 Device Recall INFUSE Bone Graft X SMALL KIT 42

Figure 2 15: Class 3 Device Recall Euflexxa (1 sodium hyaluronate) 43

Figure 2 16: Evaluation of DTRAX Graft in Patients with Cervical Degenerative Disc Disease 44

Figure 2 17: Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites. 44

Figure 2 18: Assessing Physical Activity Levels of Patients Following HTO. 45

Figure 2 19: Evaluation of Fusion Rate Using K2M VESUVIUS® Demineralized Fibers with K2M EVEREST® Spinal System 45

Figure 2 20: Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation 46

Figure 2 21: Synthetic Bone Graft Substitute vs. Autologous Spongiosa in Revision Anterior Cruciate Ligament Reconstruction 46

Figure 2 22: Cerament Treatment of Fracture Defects (CERTiFy) 47

Figure 2 23: Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute (BAGvsTCP) 47

Figure 2 24: Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™ 48

Figure 2 25: AttraX® Putty vs. Autograft in XLIF® 49

Figure 2 26: Comparison of nanOss Bioactive with Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine 49

Figure 2 27: Assessment of nanOss Bioactive 3D in the Posterolateral Spine 50

Figure 2 28: Assessment of Ridge Preservation Using Moldable Beta-tricalcium Phosphate Bone Grafting System 50

Figure 2 29: Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy 51

Figure 2 30: Efficacy and Safety of SurgiFill™ on Spinal Fusion 51

Figure 2 31: Assessment of HydroxyColl Bone Graft Substitute in High Tibial Osteotomy Wedge Grafting. (HColl_HTO) 52

Figure 2 32: Outcomes of the Evans Calcaneal Lengthening Based on Bone Grafting Material 52

Figure 2 33: Deproteinized Bovine Bone in Alveolar Bone Critical Size Defect (>2cm) Secondary to Cyst Removal 53

Figure 2 34: A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP® 53

Figure 2 35: The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation 54

Figure 2 36: Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2 54

Figure 2 37: Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery (Intebody) 55

Figure 2 38: A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 55

Figure 2 39: Clinical Study of INFUSE® Bone Graft Compared to Autogenous Bone Graft for Vertical Ridge Augmentation 56

Figure 2 40: Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment 56

Figure 2 41: RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion (AxA) 57

Figure 2 42: Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft 57

Figure 2 43: rhBMP-2 vs Autologous Bone Grafting for the Treatment of Non-union of the Docking Site in Tibial Bone Transport 58

Figure 2 44: Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery 58

Figure 2 45: Study of Cingal™ for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide at 39 Weeks Follow-Up (Cingal17-02) 59

Figure 2 46: HyaloFAST Trial for Repair of Articular Cartilage in the Knee (FastTRACK) 59

Figure 2 47: Effectiveness of Two Hyaluronic Acids in Osteoarthritis of the Knee 60

Figure 2 48: The Effect of Topical Application of Hyaluronic Acid on Immediate Dental Implant 61

Figure 2 49: To Look at the Characteristics of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knees After Hyaluronic Acid Injection 61

Figure 2 50: Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Humans 62

Figure 2 51: Two Weekly Intra-articular Hyaluronan Knee Injections, Given One Week Apart, of HYMOVIS Combined With a Physical Exercise Program (PEP) Compared to PEP Alone, in a Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA) 62

Figure 2 52: Comparative Assessment of Viscosupplementation With Polynucleotides and Hyaluronic Acid (PNHA1401) 63

Figure 2 53: Trial Comparing Botulin Toxin Versus Hyaluronic Acid by Intra-articular Injection (GOTOX) 63

Figure 2 54: Trial to Assess the Structural Effect and Long-term Symptomatic Relief of Intra-articular Injections of HA (ViscOA) 64

Figure 3 1: Currency Exchange Rate, 2019 67

Figure 3 2: Orthopedic Biomaterials Market by Segment, India, 2016 – 2026 (US$M) 69

Figure 3 3: Orthopedic Biomaterials Market by Segment, India, 2016 – 2026 (IN₹M) 70

Figure 3 4: Orthopedic Biomaterials Market Growth by Segment, India, 2016 – 2026 74

Figure 3 5: Drivers and Limiters, Orthopedic Biomaterials Market, India, 2019 77

Figure 3 6: Leading Competitors, Orthopedic Biomaterials Market, India, 2019 81

Figure 3 7: SWOT Analysis, Anika Therapeutics (1 of 2) 103

Figure 3 8: SWOT Analysis, Anika Therapeutics (2 of 2) 104

Figure 3 9: SWOT Analysis, Bioventus (1 of 2) 105

Figure 3 10: SWOT Analysis, Bioventus (2 of 2) 106

Figure 3 11: SWOT Analysis, DePuy Synthes 107

Figure 3 12: SWOT Analysis, Ferring Pharmaceuticals 108

Figure 3 13: SWOT Analysis, Fidia Pharmaceuticals 109

Figure 3 14: SWOT Analysis, Genzyme (Sanofi) 110

Figure 3 15: SWOT Analysis, Harvest Technologies 111

Figure 3 16: SWOT Analysis, Integra LifeSciences 112

Figure 3 17: SWOT Analysis, Medtronic 113

Figure 3 18: SWOT Analysis, MTF 114

Figure 3 19: SWOT Analysis, NuVasive 115

Figure 3 20: SWOT Analysis, Orthofix 116

Figure 3 21: SWOT Analysis, RTI Surgical 117

Figure 3 22: SWOT Analysis, Stryker 118

Figure 3 23: SWOT Analysis, Vericel Corporation 119

Figure 3 24: SWOT Analysis, Zimmer Biomet (1 of 2) 120

Figure 3 25: SWOT Analysis, Zimmer Biomet (2 of 2) 121

Figure 4 1: Units per Procedure by Indication, Bone Graft Substitute Market, India, 2016– 2026 123

Figure 4 2: Orthopedic Biomaterials Procedures by Segment, India, 2016 – 2026 124

Figure 4 3: Orthopedic Bone Grafting Procedures by Material, India, 2016 – 2026 126

Figure 4 4: Autograft Procedures by Indication, India, 2016 – 2026 (1 of 2) 128

Figure 4 5: Autograft Procedures by Indication, India, 2016 – 2026 (2 of 2) 129

Figure 4 6: Allograft Procedures by Indication, India, 2016 – 2026 (1 of 2) 131

Figure 4 7: Allograft Procedures by Indication, India, 2016 – 2026 (2 of 2) 132

Figure 4 8: DBM Allograft Procedures by Indication, India, 2016 – 2026 (1 of 2) 134

Figure 4 9: DBM Allograft Procedures by Indication, India, 2016 – 2026 (2 of 2) 135

Figure 4 10: Synthetic Procedures by Indication, India, 2016 – 2026 (1 of 2) 137

Figure 4 11: Synthetic Procedures by Indication, India, 2016 – 2026 (2 of 2) 138

Figure 4 12: Orthopedic Bone Grafting Procedures by Indication, India, 2016 – 2026 (1 of 2) 140

Figure 4 13: Orthopedic Bone Grafting Procedures by Indication, India, 2016 – 2026 (2 of 2) 141

Figure 4 14: Orthopedic Growth Factor Procedures, India, 2016 – 2026 143

Figure 4 15: Hyaluronic Acid Viscosupplementation Procedures by Injection Cycle, India,  2016 – 2026 145

Figure 5 1: Orthopedic Bone Graft Substitute Market by Material, India, 2016 – 2026 (US$M) 148

Figure 5 2: Orthopedic Bone Graft Substitute Market by Material, India, 2016 – 2026 (IN₹M) 149

Figure 5 3: Orthopedic Bone Graft Substitute Market by Indication, India, 2016 – 2026 (US$M) 154

Figure 5 4: Orthopedic Bone Graft Substitute Market by Indication, India, 2016 – 2026 (IN₹M) 155

Figure 5 5: Total Orthopedic Bone Graft Substitute Market, India, 2016 – 2026 159

Figure 5 6: Allograft Bone Graft Substitute Market, India, 2016 – 2026 161

Figure 5 7: Allograft Bone Graft Substitute Market by Indication, India, 2016 – 2026 (US$M) 163

Figure 5 8: Spine Allograft Market, India, 2016 – 2026 165

Figure 5 9: Cervical Spine Allograft Market, India, 2016 – 2026 166

Figure 5 10: Thoracolumbar Spine Allograft Market, India, 2016 – 2026 167

Figure 5 11: Trauma Allograft Market, India, 2016 – 2026 168

Figure 5 12: Non-Union Trauma Allograft Market, India, 2016 – 2026 169

Figure 5 13: Fresh Fracture Trauma Allograft Market, India, 2016 – 2026 170

Figure 5 14: Large Joint Reconstruction Allograft Market, India, 2016 – 2026 171

Figure 5 15: Hip Reconstruction Allograft Market, India, 2016 – 2026 172

Figure 5 16: Knee Reconstruction Allograft Market, India, 2016 – 2026 173

Figure 5 17: Foot Reconstruction Allograft Market, India, 2016 – 2026 174

Figure 5 18: Craniomaxillofacial Allograft Market, India, 2016 – 2026 175

Figure 5 19: Oncology Allograft Market, India, 2016 – 2026 176

Figure 5 20: Demineralized Bone Matrix Allograft Bone Graft Substitute Market,  India, 2016 – 2026 177

Figure 5 21: Demineralized Bone Matrix Allograft Bone Graft Substitute Market by Indication, India, 2016 – 2026 (US$M) 179

Figure 5 22: Spine DBM Allograft Market, India, 2016 – 2026 181

Figure 5 23: Cervical Spine DBM Allograft Market, India, 2016 – 2026 182

Figure 5 24: Thoracolumbar Spine DBM Allograft Market, India, 2016 – 2026 183

Figure 5 25: Trauma DBM Allograft Market, India, 2016 – 2026 184

Figure 5 26: Non-Union Trauma DBM Allograft Market, India, 2016 – 2026 185

Figure 5 27: Fresh Fracture Trauma DBM Allograft Market, India, 2016 – 2026 186

Figure 5 28: Large Joint Reconstruction DBM Allograft Market, India, 2016 – 2026 187

Figure 5 29: Hip Reconstruction DBM Allograft Market, India, 2016 – 2026 188

Figure 5 30: Knee Reconstruction DBM Allograft Market, India, 2016 – 2026 189

Figure 5 31: Foot Reconstruction DBM Allograft Market, India, 2016 – 2026 190

Figure 5 32: Craniomaxillofacial DBM Allograft Market, India, 2016 – 2026 191

Figure 5 33: Oncology DBM Allograft Market, India, 2016 – 2026 192

Figure 5 34: Synthetic Bone Graft Substitute Market, India, 2016 – 2026 193

Figure 5 35: Synthetic Bone Graft Substitute Market by Indication, India, 2016 – 2026 (US$M) 195

Figure 5 36: Spine Synthetic Market, India, 2016 – 2026 197

Figure 5 37: Cervical Spine Synthetic Market, India, 2016 – 2026 198

Figure 5 38: Thoracolumbar Spine Synthetic Market, India, 2016 – 2026 199

Figure 5 39: Trauma Synthetic Market, India, 2016 – 2026 200

Figure 5 40: Non-Union Trauma Synthetic Market, India, 2016 – 2026 201

Figure 5 41: Fresh Fracture Trauma Synthetic Market, India, 2016 – 2026 202

Figure 5 42: Large Joint Reconstruction Synthetic Market, India, 2016 – 2026 203

Figure 5 43: Hip Reconstruction Synthetic Market, India, 2016 – 2026 204

Figure 5 44: Knee Reconstruction Synthetic Market, India, 2016 – 2026 205

Figure 5 45: Foot Reconstruction Synthetic Market, India, 2016 – 2026 206

Figure 5 46: Craniomaxillofacial Synthetic Market, India, 2016 – 2026 207

Figure 5 47: Oncology Synthetic Market, India, 2016 – 2026 208

Figure 5 48: Spine Bone Graft Substitute Market, India, 2016 – 2026 209

Figure 5 49: Cervical Spine Bone Graft Substitute Market, India, 2016 – 2026 211

Figure 5 50: Thoracolumbar Spine Bone Graft Substitute Market, India, 2016 – 2026 213

Figure 5 51: Trauma Bone Graft Substitute Market, India, 2016 – 2026 215

Figure 5 52: Non-Union Trauma Bone Graft Substitute Market, India, 2016 – 2026 217

Figure 5 53: Fresh Fracture Trauma Bone Graft Substitute Market, India, 2016 – 2026 219

Figure 5 54: Large Joint Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 221

Figure 5 55: Hip Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 223

Figure 5 56: Knee Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 225

Figure 5 57: Foot Reconstruction Bone Graft Substitute Market, India, 2016 – 2026 227

Figure 5 58: Craniomaxillofacial Bone Graft Substitute Market, India, 2016 – 2026 229

Figure 5 59: Oncology Bone Graft Substitute Market, India, 2016 – 2026 231

Figure 5 60: Drivers and Limiters, Orthopedic Bone Graft Substitute Market, India, 2019 234

Figure 5 61: Leading Competitors, Orthopedic Bone Graft Substitute Market, India, 2019 236

Figure 6 1: Orthopedic Growth Factor Market, India, 2016 – 2026 240

Figure 6 2: Drivers and Limiters, Orthopedic Growth Factor Market, India, 2019 243

Figure 6 3: Leading Competitors, Orthopedic Growth Factor Market, India, 2019 244

Figure 7 1: Hyaluronic Acid Viscosupplementation Market by Segment, India, 2016 – 2026 (US$M) 248

Figure 7 2: Hyaluronic Acid Viscosupplementation Market by Segment, India, 2016 – 2026 (IN₹M) 249

Figure 7 3: Total Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 253

Figure 7 4: Single-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 255

Figure 7 5: Three-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 257

Figure 7 6: Five-Injection Hyaluronic Acid Viscosupplementation Market, India, 2016 – 2026 259

Figure 7 7: Drivers and Limiters, Hyaluronic Acid Viscosupplementation Market, India, 2019 262

Figure 7 8: Leading Competitors, Hyaluronic Acid Viscosupplementation Market, India, 2019 265

iData’s 9-Step Research Methodology

Our reports follow an in-depth 9-step methodology which focuses on the following research systems:

• Original primary research that consists of the most up-to-date market data
• Strong foundation of quantitative and qualitative research
• Focused on the needs and strategic challenges of the industry participants

Step 1: Project Initiation & Team Selection During this preliminary investigation, all staff members involved in the industry discusses the topic in detail.

Step 2: Prepare Data Systems and Perform Secondary Research The first task of the research team is to prepare for the data collection process: Filing systems and relational databases are developed as needed.

Step 3: Preparation for Interviews & Questionnaire Design The core of all iData research reports is primary market research. Interviews with industry insiders represent the single most reliable way to obtain accurate, current data about market conditions, trends, threats and opportunities.

Step 4: Performing Primary Research At this stage, interviews are performed using contacts and information acquired in the secondary research phase.

Step 5: Research Analysis: Establishing Baseline Estimates Following the completion of the primary research phase, the collected information must be synthesized into an accurate view of the market status. The most important question is the current state of the market.

Step 6: Market Forecast and Analysis iData Research uses a proprietary method to combine statistical data and opinions of industry experts to forecast future market values.

Step 7: Identify Strategic Opportunities iData analysts identify in broad terms why some companies are gaining or losing share within a given market segment.

Step 8: Final Review and Market Release An integral part of the iData research methodology is a built-in philosophy of quality control and continuing improvement is integral to the iData philosophy.

Step 9: Customer Feedback and Market Monitoring iData philosophy of continuous improvement requires that reports and consulting projects be monitored after release for customer feedback and market accuracy.

Click Here to Read More About Our Methodology