Orthopedic Bone Graft Substitute Market Size, Share, and Trends Analysis | Global | 2025-2031 | MedCore | Includes: Allograft Market, Demineralized Bone Matrix Market, and 1 more

  • Year: 2025
  • Scope: 10 Years
  • Region: Global
  • Published Date: 01/24/2025
  • Type: MedCore

Product Description

The global bone graft substitute market was valued at approximately $2.83 billion in 2024. This is expected to increase over the forecast period at a CAGR of 4.1% to reach approximately $3.75 billion.

The full report suite on the global market for bone graft substitute (BGS) includes allograft BGS, demineralized bone matrix (DBM) allograft BGS and synthetic BGS. The market is further analyzed by unit type. Specifically, they are divided by nine types of indication: cervical, thoracolumbar spine, non-union trauma, fresh facture trauma, hip bone, knee bone, foot bone, craniomaxillofacial and oncology.

This report includes data for 65 countries across 7 different regions. These regions are North America, Latin America, Western Europe, Central & Eastern Europe, Middle East, Asia-Pacific, and Africa.

DATA TYPES INCLUDED

  • Unit Sales, Average Selling Prices, Market Size & Growth Trends
  • Procedure Numbers
  • Market Drivers & Limiters
  • Market Forecasts Until 2031, and Historical Data to 2021
  • Recent Mergers & Acquisitions
  • Company Profiles and Product Portfolios
  • Leading Competitors

GLOBAL ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET INSIGHTS

Global Orthopedic Bone Graft Substitute Market GrowthThe BGS market experienced a notable decline in sales due to the COVID-19 pandemic. The primary driver was the widespread cancellation and postponement of elective surgeries, which significantly disrupted the industry’s ecosystem. While this downturn was temporary, the impact in 2020 was substantial, with many companies incurring unprecedented losses. However, the market demonstrated resilience and managed to recover notably by 2022, returning to its trajectory of steady growth.

GLOBAL ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET SHARE INSIGHTSTop Competitors Global Orthopedic Bone Graft Substitute Market

  • Medtronic was the leader of the BGS market due to a leading share in the demineralized bone graft market, as well as the synthetic bone graft market. Medtronic’s Grafton® is the first fiber-based DBM allograft BGS and remains one of the most popular products in this market. Medtronic also sells four versions of its synthetic MASTERGRAFT® product: granules, a moldable putty, a flexible strip and MASTERGRAFT® Matrix EXT.
  • Stryker held the second-leading position in the BGS market by offering a number of products, including Vitoss™, ALLOMATRIX®, FUSIONFLEX® and PRO-STIM®.
  • DePuy Synthes was the third-leading competitor in the BGS market in 2024. The company competes in the market with its DBX® DBM product line, as well as chronOS® synthetic BGS.

GLOBAL ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET SEGMENTATION SUMMARY

  • Allograft Market – Further Segmented Into:
    • Indication Type: Spine, Trauma, Oncology, Craniomaxillofacials, Large Joint Reconstruction, and Foot Reconstructions.
  • Demineralized Bone Matrix Market – Further Segmented Into:
    • Indication Type: Spine, Trauma Oncology, Craniomaxillofacials, Large Joint Reconstruction, and Foot Reconstructions.
  • Synthetic Market – Further Segmented Into:
    • Indication Type: Spine, Trauma Oncology, Craniomaxillofacials, Large Joint Reconstruction, and Foot Reconstructions.

GLOBAL RESEARCH SCOPE

Report Attribute Details
Regions North America(Canada, United States)
Latin America(Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Guatemala, Mexico, Panama, Paraguay, Peru, Puerto Rico, Uruguay, Venezuela)
Western Europe(Austria, Benelux, France, Germany, Italy, Portugal, Scandinavia, Spain, Switzerland, United Kingdom)
Central & Eastern Europe(Azerbaijan, Baltic States, Belarus, Bulgaria, Croatia, Czech Republic, Georgia, Greece, Hungary, Kazakhstan, Poland, Romania, Russia, Serbia, Slovakia, Slovenia, Turkey, Ukraine)
Middle East(Bahrain, Iran, Israel, Kuwait, Oman, Qatar, Saudi Arabia, United Arab Emirates)
Asia Pacific(Australia, Cambodia, China, Hong Kong, India, Indonesia, Japan, Kyrgyzstan, Macao, Malaysia, Mongolia, Myanmar, New Zealand, Pakistan, Philippines, Singapore, South Korea, Sri Lanka, Taiwan, Thailand, Uzbekistan, Vietnam)
Africa(Algeria, Egypt, Ethiopia, Ghana, Kenya, Libya, Morocco, Nigeria, South Africa, Sudan, Uganda)
Base Year 2024
Forecast 2025-2031
Historical Data 2021-2023
Quantitative Coverage Procedure Numbers, Market Size, Market Shares, Market Forecasts, Market Growth Rates, Units Sold, and Average Selling Prices.
Qualitative Coverage COVID19 Impact, Market Growth Trends, Market Limiters, Competitive Analysis & SWOT for Top Competitors, Mergers & Acquisitions, Company Profiles, Product Portfolios, FDA Recalls, Disruptive Technologies, Disease Overviews.
Data Sources Primary Interviews with Industry Leaders, Government Physician Data, Regulatory Data, Hospital Private Data, Import & Export Data, iData Research Internal Database.

 

FREE Sample Report

4.1 Executive Summary
4.1.1 Global Orthopedic Bone Graft Substitute Market Overview
4.1.2 Competitive Analysis
4.1.3 Regions Included
4.2 Introduction
4.3 Procedure Numbers
4.3.1 Total Orthopedic Bone Grafting Procedures
4.3.2 Allograft Procedures
4.3.3 Demineralized Bone Matrix Procedures
4.3.4 Synthetic Procedures
4.4 Market Overview
4.4.1 By Segment
4.4.2 By Region
4.5 Market Analysis and Forecast
4.5.1 Total Orthopedic Bone Graft Substitute Market
4.5.2 Allograft Bone Graft Substitute Market
4.5.3 Demineralized Bone Matrix Allograft Bone Graft Substitute Market
4.5.4 Synthetic Bone Graft Substitute Market
4.5.4.1 Synthetic Bone Graft Substitute Market by Generation Type
4.6 Unit Analysis
4.6.1 Allograft Bone Graft Substitute Unit Analysis
4.6.1.1 Allograft Bone Graft Substitute Units Sold by Indication
4.6.1.1.1 Spine Allograft Bone Graft Substitute Units Sold
4.6.1.1.2 Trauma Allograft Bone Graft Substitute Units Sold
4.6.1.1.3 Large Joint Reconstruction Allograft Bone Graft Substitute Units Sold
4.6.2 Demineralized Bone Matrix Allograft Bone Graft Substitute Unit Analysis
4.6.2.1 Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold by Indication
4.6.2.1.1 Spine Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
4.6.2.1.2 Trauma Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
4.6.2.1.3 Large Joint Reconstruction Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
4.6.3 Synthetic Bone Graft Substitute Unit Analysis
4.6.3.1 Synthetic Bone Graft Substitute Units Sold by Indication
4.6.3.1.1 Spine Synthetic Bone Graft Substitute Units Sold
4.6.3.1.2 Trauma Synthetic Bone Graft Substitute Units Sold
4.6.3.1.3 Large Joint Reconstruction Synthetic Bone Graft Substitute Units Sold
4.7 Drivers and Limiters
4.7.1 Market Drivers
4.7.2 Market Limiters
4.8 Competitive Market Share Analysis
·         AbbVie ·         LCA Pharma
·         Acumed ·         LifeLink Tissue Bank
·         AlloSource ·         LifeNet Health
·         Alphatec Spine ·         Meda Pharma
·         Anika Therapeutics ·         Medtronic
·         Arthrex ·         MTF
·         B. Braun Melsungen ·         Novabone
·         Baxter ·         Nuo Therapeutics
·         Berkeley Advanced Biomaterials ·         Octane Medical
·         Biocell ·         Orthocell Ltd.
·         Biocomposites ·         OrthogenRx
·         Biogennix ·         Orthofix
·         Bioiberica ·         Osteogenics
·         Biomatlante ·         OsteoMed
·         Biotissue Technologies ·         Paragon 28
·         Bioventus ·         Plasmaconcept
·         Bonalive ·         PromoCell
·         Celling Biosciences ·         Rebone Biomaterials
·         Cerapedics ·         Recordati
·         Cingal ·         Regenexx
·         Croma-Pharma ·         Regenity Biosciences
·         CO.DON GmbH ·         RTI Surgical
·         CONMED ·         Sanofi
·         Curasan ·         Sartorius CellGenix GmbH
·         DCI Donor Services ·         Seikagaku
·         DePuy Synthes ·         Smith & Nephew
·         Documedica ·         Solvita
·         Elutia Inc. ·         Spinal Elements
·         Exactech ·         Stella Pharmaceuticals
·         Ferring Pharmaceuticals ·         Stryker
·         Fidia ·         Takara Bio
·         Finceramica ·         Tedec-Meiji
·         Geistlich ·         Terumo
·         Globus Medical/NuVasive ·         Teva Pharmaceutical
·         Hanmi Pharmaceutical ·         ThermoGenesis
·         Healiva ·         TRB Chemedica
·         IBSA Pharma ·         Viatris
·         Integra LifeSciences ·         Vericel
·         Isto Biologics ·         Vivex
·         Kolon Tissuegene ·         Xtant Medical
·         Kuros ·         Zimmer Biomet
Chart 4‑1: Orthopedic Bone Graft Substitute Market, Global, 2024 & 2031
Chart 4‑2: Orthopedic Bone Graft Substitute Procedures, Global, 2024
Chart 4‑3: Orthopedic Bone Grafting Procedures by Segment, Global, 2021– 2031
Chart 4‑4: Orthopedic Bone Graft Substitute Device Market by Segment, Global, 2021 – 2031
Chart 4‑5: Orthopedic Bone Graft Substitute Device Market by Region, Global, 2021 – 2031
Chart 4‑6: Leading Competitors, Orthopedic Bone Graft Substitute Market, Global, 2024
Figure 4‑1: Orthopedic Bone Graft Substitute Regions Covered, Global (1 of 2)
Figure 4‑2: Orthopedic Bone Graft Substitute Regions Covered, Global (2 of 2)
Figure 4‑3: Orthopedic Bone Grafting Procedures by Segment, Global, 2021 – 2031
Figure 4‑4: Orthopedic Bone Grafting Procedures by Region, Global, 2021 – 2031
Figure 4‑5: Orthopedic Bone Grafting Procedures by Country, North America, 2021 – 2031
Figure 4‑6: Orthopedic Bone Grafting Procedures by Country, Latin America, 2021 – 2031 (1 of 2)
Figure 4‑7: Orthopedic Bone Grafting Procedures by Country, Latin America, 2021 – 2031 (2 of 2)
Figure 4‑8: Orthopedic Bone Grafting Procedures by Country, Western Europe, 2021– 2031
Figure 4‑9: Orthopedic Bone Grafting Procedures by Country, Central & Eastern Europe, 2021 – 2031 (1 of 2)
Figure 4‑10: Orthopedic Bone Grafting Procedures by Country, Central & Eastern Europe, 2021 – 2031 (2 of 2)
Figure 4‑11: Orthopedic Bone Grafting Procedures by Country, Middle East, 2021 – 2031
Figure 4‑12: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021– 2031 (1 of 3)
Figure 4‑13: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021 – 2031 (2 of 3)
Figure 4‑14: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021 – 2031 (3 of 3)
Figure 4‑15: Orthopedic Bone Grafting Procedures by Country, Africa, 2021 – 2031
Figure 4‑16: Allograft Procedures by Region, Global, 2021– 2031
Figure 4‑17: Allograft Procedures by Country, North America, 2021– 2031
Figure 4‑18: Allograft Procedures by Country, Latin America, 2021– 2031 (1 of 2)
Figure 4‑19: Allograft Procedures by Country, Latin America, 2021– 2031 (2 of 2)
Figure 4‑20: Allograft Procedures by Country, Western Europe, 2021 – 2031
Figure 4‑21: Allograft Procedures by Country, Central & Eastern Europe, 2021 – 2031 (1 of 2)
Figure 4‑22: Allograft Procedures by Country, Central & Eastern Europe, 2021 – 2031 (2 of 2)
Figure 4‑23: Allograft Procedures by Country, Middle East, 2021– 2031
Figure 4‑24: Allograft Procedures by Country, Asia-Pacific, 2021 – 2031 (1 of 3)
Figure 4‑25: Allograft Procedures by Country, Asia-Pacific, 2021 – 2031 (2 of 3)
Figure 4‑26: Allograft Procedures by Country, Asia-Pacific, 2021 – 2031 (3 of 3)
Figure 4‑27: Allograft Procedures by Country, Africa, 2021– 2031
Figure 4‑28: Demineralized Bone Matrix Procedures by Region, Global, 2021– 2031
Figure 4‑29: Demineralized Bone Matrix Procedures by Country, North America, 2021– 2031
Figure 4‑30: Demineralized Bone Matrix Procedures by Country, Latin America, 2021– 2031 (1 of 2)
Figure 4‑31: Demineralized Bone Matrix Procedures by Country, Latin America, 2021– 2031 (2 of 2)
Figure 4‑32: Demineralized Bone Matrix Procedures by Country, Western Europe, 2021 – 2031
Figure 4‑33: Demineralized Bone Matrix Procedures by Country, Central & Eastern Europe, 2021 – 2031 (1 of 2)
Figure 4‑34: Demineralized Bone Matrix Procedures by Country, Central & Eastern Europe, 2021 – 2031 (2 of 2)
Figure 4‑35: Demineralized Bone Matrix Procedures by Country, Middle East, 2021 – 2031
Figure 4‑36: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021– 2031 (1 of 3)
Figure 4‑37: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021– 2031 (2 of 3)
Figure 4‑38: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021 – 2031 (3 of 3)
Figure 4‑39: Demineralized Bone Matrix Procedures by Country, Africa, 2021 – 2031
Figure 4‑40: Synthetic Procedures by Region, Global, 2021 – 2031
Figure 4‑41: Synthetic Procedures by Country, North America, 2021 – 2031
Figure 4‑42: Synthetic Procedures by Country, Latin America, 2021 – 2031 (1 of 2)
Figure 4‑43: Synthetic Procedures by Country, Latin America, 2021 – 2031 (2 of 2)
Figure 4‑44: Synthetic Procedures by Country, Western Europe, 2021– 2031
Figure 4‑45: Synthetic Procedures by Country, Central & Eastern Europe, 2021 – 2031 (1 of 2)
Figure 4‑46: Synthetic Procedures by Country, Central & Eastern Europe, 2021 – 2031 (2 of 2)
Figure 4‑47: Synthetic Procedures by Country, Middle East, 2021 – 2031
Figure 4‑48: Synthetic Procedures by Country, Asia-Pacific, 2021 – 2031 (1 of 3)
Figure 4‑49: Synthetic Procedures by Country, Asia-Pacific, 2021 – 2031 (2 of 3)
Figure 4‑50: Synthetic Procedures by Country, Asia-Pacific, 2021 – 2031 (3 of 3)
Figure 4‑51: Synthetic Procedures by Country, Africa, 2021 – 2031
Figure 4‑52: Orthopedic Bone Graft Substitute Device Market by Segment, Global, 2021 – 2031 (US$M)
Figure 4‑53: Orthopedic Bone Graft Substitute Device Market by Region, Global, 2021 – 2031 (US$M)
Figure 4‑54: Orthopedic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑55: Units Sold by Region, Orthopedic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑56: Average Selling Price by Region, Orthopedic Bone Graft Substitute Market, Global, 2021– 2031 (US$)
Figure 4‑57: Market Value by Region, Orthopedic Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑58: Allograft Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑59: Units Sold by Region, Allograft Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑60: Average Selling Price by Region, Allograft Bone Graft Substitute Market, Global, 2021 – 2031 (US$)
Figure 4‑61: Market Value by Region, Allograft Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑62: Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑63: Units Sold by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑64: Average Selling Price by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 – 2031 (US$)
Figure 4‑65: Market Value by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑66: Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑67: Units Sold by Region, Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑68: Average Selling Price by Region, Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$)
Figure 4‑69: Market Value by Region, Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑70: Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑71: Units Sold by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑72: Average Selling Price by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$)
Figure 4‑73: Market Value by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑74: Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑75: Units Sold by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031
Figure 4‑76: Average Selling Price by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$)
Figure 4‑77: Market Value by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 – 2031 (US$M)
Figure 4‑78: Allograft Bone Graft Substitute Units Sold by Indication, Global, 2021 – 2031
Figure 4‑79: Spine Allograft Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑80: Trauma Allograft Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑81: Large Joint Reconstruction Allograft Bone Graft Substitute Units Sold, Global, 2021– 2031
Figure 4‑82: Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold by Indication, Global, 2021 – 2031
Figure 4‑83: Spine Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑84: Trauma Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑85: Large Joint Reconstruction Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑86: Synthetic Bone Graft Substitute Units Sold by Indication, Global, 2021 – 2031
Figure 4‑87: Spine Synthetic Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑88: Trauma Synthetic Bone Graft Substitute Units Sold, Global, 2021 – 2031
Figure 4‑89: Large Joint Reconstruction Synthetic Bone Graft Substitute Units Sold, Global,  2021 – 2031
Figure 4‑90: Leading Competitors, Orthopedic Bone Graft Substitute Market, Global, 2024

iData’s 9-Step Research Methodology

Our reports follow an in-depth 9-step methodology which focuses on the following research systems:

  • Original primary research that consists of the most up-to-date market data
  • Strong foundation of quantitative and qualitative research
  • Focused on the needs and strategic challenges of the industry participants

Step 1: Project Initiation & Team Selection During this preliminary investigation, all staff members involved in the industry discusses the topic in detail.

Step 2: Prepare Data Systems and Perform Secondary Research The first task of the research team is to prepare for the data collection process: Filing systems and relational databases are developed as needed.

Step 3: Preparation for Interviews & Questionnaire Design The core of all iData research reports is primary market research. Interviews with industry insiders represent the single most reliable way to obtain accurate, current data about market conditions, trends, threats and opportunities.

Step 4: Performing Primary Research At this stage, interviews are performed using contacts and information acquired in the secondary research phase.

Step 5: Research Analysis: Establishing Baseline Estimates Following the completion of the primary research phase, the collected information must be synthesized into an accurate view of the market status. The most important question is the current state of the market.

Step 6: Market Forecast and Analysis iData Research uses a proprietary method to combine statistical data and opinions of industry experts to forecast future market values.

Step 7: Identify Strategic Opportunities iData analysts identify in broad terms why some companies are gaining or losing share within a given market segment.

Step 8: Final Review and Market Release An integral part of the iData research methodology is a built-in philosophy of quality control and continuing improvement is integral to the iData philosophy.

Step 9: Customer Feedback and Market Monitoring iData philosophy of continuous improvement requires that reports and consulting projects be monitored after release for customer feedback and market accuracy.

Click Here to Read More About Our Methodology

Explore Options

Report Summary

FREE

Select License Type

  • 2025
  • 10 Years
  • Global
  • 01/24/2025
  • MedCore
SKU: iDATA_GLOB25_MC_BGS Categories: , , , , , , , , ,
Request Sample Sheets Request Customization
Related Reports
+

REQUEST SAMPLE SHEETS

+

REQUEST CUSTOMIZATION

+

Free Sample Report Form

+

See Report Summary

0
    0
    Your Cart
    Your cart is emptyReturn to Report Library