Anti-Adhesion Products Market Analysis | Japan | 2016-2022 | MedCore
- Year: 2016
- Scope: 2012-2022
- Region: Japan
- Pages: 29
- Published Date: 6/1/2016
- Type: MedCore
Adhesions are often thought of as internal scar tissue and are a side effect of the bodys natural healing process. For example, up to 93% of patients who undergo intra-abdominal surgery develop adhesions. The majority of adhesions are asymptomatic; however, approximately 5% of adhesions result in severe symptoms such as pain, small bowel obstruction (SBO), range of motion restriction and/or infertility. While only 5% of adhesions result in symptoms severe enough to require further treatment, as many as 30% are thought to cause low level discomfort that is tolerated by the patient. Adhesions are believed to be responsible for approximately 65% of all SBO, 35% of chronic pelvic pain and 20% of infertility diagnoses. There are a number of different methods that surgeons use to reduce the incidence of adhesions. The most effective way is to perform laparoscopic procedures whenever possible, as they carry a much lower risk of symptomatic adhesion formation. In addition, surgeons attempt to minimize tissue necrosis, providing meticulous hemostasis, liberally irrigating the abdominal cavity and using non-reactive suture materials. In some situations, drugs that inhibit the inflammatory response, such as corticosteroids, non-steroidal anti-inflammatory, pentoxifylline and calcium channel blockers have been used. However, the most effective method of reducing adhesions has been determined to be the use of adhesion barriers. The first of currently used products entered the market in 1989 and was made out of oxidized regenerated cellulose (ORC). It is absorbed within four weeks of application. Seprafilm® by Genzyme consists of sodium hyaluronate and carboxymethylcellulose, forming a film that becomes a hydrated gel 24 to 48 hours after placement.
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