| Figure 1-1: Neurological Device Market Share Ranking by Segment, U S , 2021 (1 of 2) 4 |
| Figure 1-2: Neurological Device Market Share Ranking by Segment, U S , 2021 (2 of 2) 4 |
| Figure 1-3: Companies Researched in this Report, U S , 2021 5 |
| Figure 1-4: Factors Impacting the Neurological Device Market by Segment, U S (1 of 2) 6 |
| Figure 1-5: Factors Impacting the Neurological Device Market by Segment, U S (2 of 2) 7 |
| Figure 1-6: Recent Events in the Neurological Device Market, U S , 2018 – 2021 8 |
| Figure 1-1: Neurological Device Procedures Covered 9 |
| Figure 1-2: Neurological Device Markets Covered (1 of 2) 10 |
| Figure 1-3: Neurological Device Markets Covered (2 of 2) 11 |
| Figure 1-4: Key Report Updates 12 |
| Figure 1-5: Version History 12 |
| Figure 2-1: Neurological Device Market by Segment, Worst Case Scenario, U S , 2018 – 2028 (US$M) (1 of |
| 3) 29 |
| Figure 2-2: Neurological Device Market by Segment, Worst Case Scenario, U S , 2018 – 2028 (US$M) (2 of |
| 3) 30 |
| Figure 2-3: Neurological Device Market by Segment, Worst Case Scenario, U S , 2018 – 2028 (US$M) (3 of |
| 3) 31 |
| Figure 2-4: Neurological Device Market by Segment, Base Case Scenario, U S , 2018 – 2028 (US$M) (1 of |
| 3) 32 |
| Figure 2-5: Neurological Device Market by Segment, Base Case Scenario, U S , 2018 – 2028 (US$M) (2 of |
| 3) 33 |
| Figure 2-6: Neurological Device Market by Segment, Base Case Scenario, U S , 2018 – 2028 (US$M) (3 of |
| 3) 34 |
| Figure 2-7: Neurological Device Market by Segment, Best Case Scenario, U S , 2018 – 2028 (US$M) (1 of |
| 3) 35 |
| Figure 2-8: Neurological Device Market by Segment, Best Case Scenario, U S , 2018 – 2028 (US$M) (2 of |
| 3) 36 |
| Figure 2-9: Neurological Device Market by Segment, Best Case Scenario, U S , 2018 – 2028 (US$M) (3 of |
| 3) 37 |
| Figure 3-1: Neurology Disease Overview 42 |
| Figure 4-1: Shunt Types 57 |
| Figure 4-2: Cerebrospinal Fluid Management by Company 59 |
| Figure 4-3: Detachable Coils by Company 61 |
| Figure 4-4: Liquid Embolics by Company 63 |
| Figure 4-5: Neurovascular Catheters by Company 65 |
| Figure 4-6: Neurovascular Guidewires by Company 67 |
| Figure 4-7: Neurovascular Stent by Company 69 |
| Figure 4-8: Balloon Occlusion Devices by Company 71 |
| Figure 4-9: Aneurysm Clip Devices by Company 73 |
| Figure 4-10: Neurovascular Thrombus Management Devices by Company 76 |
| Figure 4-11: Neuromodulation Devices by Company 81 |
| Figure 4-12: Intrathecal Pumps Devices by Company 83 |
| Figure 4-13: Stereotactic Devices by Company 86 |
| Figure 4-14: Neuroendoscopy by Company 89 |
| Figure 4-15: Ultrasonic Aspiration Devices by Company 90 |
| Figure 4-16: Class 2 Device Recall Natus EDS3 CSF External Drainage System 91 |
| Figure 4-17: Class 2 Device Recall Medtronic PS Medical CSFFlow Control Valves 91 |
| Figure 4-18: Class 2 Device Recall MicroVention Terumo Microplex 10, Helical 10 Soft 92 |
| Figure 4-19: Class 2 Device Recall MicroVention Terumo HydroFrame 10 and 18 92 |
| Figure 4-20: Class 2 Device Recall MicroVention Terumo Microplex 10, Compass 10 92 |
| Figure 4-21: Class 2 Device Recall MicroVention Terumo HydroSoft 10, HydroSoft 3D 93 |
| Figure 4-22: Class 2 Device Recall GALAXY G3 Mini Microcoil Delivery System 93 |
| Figure 4-23: Class 2 Device Recall C315HIS Delivery Catheter 94 |
| Figure 4-24: Class 2 Device Recall MIVI Super 90 Guide Catheters 94 |
| Figure 4-25:Class 2 Device Recall MAMBA Flex 135 Microcatheter 94 |
| Figure 4-26: Class 2 Device Recall Intracranial Neurovascular Stent 95 |
| Figure 4-27: Class 2 Device Recall MIVI Super 90 Guide Catheters 96 |
| Figure 4-28: Class 2 Device Recall MAMBA Flex 135 Microcatheter 96 |
| Figure 4-29:Class 2 Device Recall 6F Launcher Guide Catheter 96 |
| Figure 4-30: Class 2 Device Recall Conquest PTA Balloon Dilatation Catheter 97 |
| Figure 4-31:Class 2 Device Recall Merci Balloon Guide Catheters 97 |
| Figure 4-32: Class 2 Device Recall Medtronic Wireless Recharger 98 |
| Figure 4-33: Class 2 Device Recall Model B352000 Percept PC BrainSense Implantable Neurostimulator 98 |
| Figure 4-34: Class 2 Device Recall A610 98 |
| Figure 4-35: Class 2 Device Recall Percept PC Implantable Neurostimulator (INS) 98 |
| Figure 4-36: Class 2 Device Recall KARL STORZ NEUROFIBERSCOPE 99 |
| Figure 4-37: Class 2 Device Recall Karl Storz NeuroFiberscope 99 |
| Figure 4-38: Class 2 Device Recall FLEXIBLE NEURO FIBERSCOPE 99 |
| Figure 4-39: Class 2 Device Recall Stealth Autoguide Tracker, Model: 28248 100 |
| Figure 4-40:Class 2 Device Recall Medtronic 100 |
| Figure 4-41: Class 2 Device Recall Polaris Spectra Camera for StealthStation S7 System 100 |
| Figure 4-42:Class 2 Device Recall Leksell Vantage Stereotactic System 100 |
| Figure 4-43: Class 2 Device Recall Leksell Vantage Stereotactic System 101 |
| Figure 4-44:Class 2 Device Recall ROSA Brain 3 0 Application Brain and ROSA One 3 1 101 |
| Figure 4-45: Class 2 Device Recall Trident Endoscopic Ultrasonic Aspiration Needle (FNA) 102 |
| Figure 4-46: Class 2 Device Recall Footswitch accessory 102 |
| Figure 4-47: Class 2 Device Recall Leica M220 F12 103 |
| Figure 4-48: Class 2 Device Recall Prometra Programmable Pump System 104 |
| Figure 4-49: Class 2 Device Recall Medtronic Synchromed II Implantable Drug Infusion Pump 104 |
| Figure 4-50: Class 2 Device Recall AXS Vecta 71 , Vecta 74 Aspiration Catheter 105 |
| Figure 4-51: Class 1 Device Recall MINDFRAME CAPTURE(TM) LP Revascularization Device 105 |
| Figure 4-52: Class 2 Device Recall Trevo XP ProVue System 105 |
| Figure 4-53: The Effect of Lumbar CSF Drainage on the Neurologic Outcome Improvement in OHCA |
| Underwent TTM 107 |
| Figure 4-54: Operative Procedures vs Endovascular Neurosurgery for Untreated Pseudotumor Trial |
| (OPEN-UP) 107 |
| Figure 4-55: Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension |
| (HYDROPTIC) 108 |
| Figure 4-56: SMART - A Prospective, Multicenter Study Assessing the Embolization of Neurovascular |
| Lesions Using the Penumbra Smart Coil 109 |
| Figure 4-57: Prospective, Randomized, Controlled, Open Label, All China, Multi-Center, Registration Trial |
| of the MICROPORT NEUROTECH Coil Embolization System for the Traetment of Intracranial Aneurysms |
| 109 |
| Figure 4-58: Transcatheter Leak Closure with Detachable Coils Following Incomplete Left Atrial |
| Appendage Closure Procedures (TREASURE) 110 |
| Figure 4-59: Middle Meningeal Artery Embolization with Liquid Embolic Agent for Treatment of Chronic |
| Subdural Hematoma 111 |
| Figure 4-60: Treatment of Cerebral Arteriovenous Malformations with SQUID Liquid Embolic Agent - The |
| CHOICE Study A Non-interventional, Prospective, Single-arm, International, Multicenter Study 111 |
| Figure 4-61: quid Liquid Embolic Agent for the Embolization of Abdominopelvic Arterial Bleeding |
| Syndrome (SQUIDperi Study) (SQUIDperi) 112 |
| Figure 4-62: Non-adhesive Liquid Embolic System in the Embolization of Cerebral Arteriovenous |
| Malformations 112 |
| Figure 4-63: SMART - A Prospective, Multicenter Study Assessing the Embolization of Neurovascular |
| Lesions Using the Penumbra Smart Coil 113 |
| Figure 4-64: Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps |
| for CSF Infusion 113 |
| Figure 4-65: Inflammatory and Infectious Diseases of the Nervous System 114 |
| Figure 4-66: Safety and Utility Profile of the Asahi Chikai Black 18 neurovascular guidewire in Large Vessel |
| Occlusive Stroke: SURE 18 Registry 115 |
| Figure 4-67: Evaluation of Safety and Performance of the Neuroform AtlasTM Stent System for |
| Intracranial Aneurysm Treatment - Post Market Clinical Follow-up 116 |
| Figure 4-68: Safety and Effectiveness of the Treatment of Wide Neck, Intracranial, Saccular Aneurysms |
| with the Next Generation Neuroform Stent System 116 |
| Figure 4-69: MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization |
| (PARADIGM-EXT) 117 |
| Figure 4-70: The Motor Network in Essential Tremor: Mechanisms of Therapy 118 |
| Figure 4-71: Wearable Neuromodulation DeVice for the TrEatment of Alzheimer's Disease (WAVE-AD) |
| 118 |
| Figure 4-72: A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in |
| Children and Adolescents Visiting the Emergency Department 119 |
| Figure 4-73: Minimally-invasive Surgery Versus Craniotomy in Patients with Supratentorial Hypertensive |
| Intracerebral Hemorrhage: A Multi-center Randomized Controlled Trial 120 |
| Figure 4-74: Minimally Invasive Treatment of Hypertensive Basal Ganglia Hemorrhage by Transfrontal |
| Keyhole Neuroendoscopy 120 |
| Figure 4-75: Phase I Study of Stereotactic Radiosurgery Dose Escalation for Brain Metastases 121 |
| Figure 4-76: Cyberknife Radiosurgery for Patients with Brain Metastases Diagnosed With Either SPACE or |
| MPRAGE Sequence - A Prospective Randomized Evaluation of Response and Toxicity 121 |
| Figure 4-77: Phase I TITE-CREM Dose Escalation Study of Fractionated Stereotactic Radiation Therapy |
| (FSRT) in Unresected Brain Metastases 122 |
| Figure 4-78: Safety and Effectiveness of SOFIA™/SOFIA™ PLUS for Direct Aspiration in Acute Ischemic |
| Stroke (SESAME) 123 |
| Figure 4-79: Feasibility Study of RapidPulseTM Aspiration System as Frontline Approach for Stroke |
| Patients (RapidPulseFS) 123 |
| Figure 4-80: A Single-Arm Objective Performance Criteria Trail For Intracranial Thrombus Aspiration |
| Catheter 124 |
| Figure 4-81: A Safety and Efficacy Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage |
| Patients Undergoing Aneurysm Clipping 125 |
| Figure 4-82: Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting |
| and Preserving Terminated Nerve Ends 126 |
| Figure 4-83: Regional Strategy for Transfer for Mechanical Thrombectomy (START) 127 |
| Figure 4-84: Evaluation of Mechanical Thrombectomy in Acute Ischemic Stroke Related to a Distal |
| Arterial Occlusion (DISCOUNT) 127 |
| Figure 5-1: Neurological Device Market by Segment, U S , 2018 – 2028 (US$M) (1 of 3) 134 |
| Figure 5-2: Neurological Device Market by Segment, U S , 2018 – 2028 (US$M) (2 of 3) 135 |
| Figure 5-3: Neurological Device Market by Segment, U S , 2018 – 2028 (US$M) (3 of 3) 136 |
| Figure 5-4: Leading Competitors, Neurological Device Market, U S , 2021 (1 of 3) 150 |
| Figure 5-5: Leading Competitors, Neurological Device Market, U S , 2021 (2 of 3) 151 |
| Figure 5-6: Leading Competitors, Neurological Device Market, U S , 2021 (3 of 3) 152 |
| Figure 5-7: SWOT Analysis, Abbott 166 |
| Figure 5-8: SWOT Analysis, B Braun 167 |
| Figure 5-9 SWOT Analysis, Boston Scientific 168 |
| Figure 5-10: SWOT Analysis, Integra LifeSciences 169 |
| Figure 5-11: SWOT Analysis, LivaNova 170 |
| Figure 5-12: SWOT Analysis, Medtronic 171 |
| Figure 5-13: SWOT Analysis, MicroVention 172 |
| Figure 5-14: SWOT Analysis, Mizuho 173 |
| Figure 5-15: SWOT Analysis, Stryker 174 |
| Figure 6-1: Neurological Procedures by Type, U S , 2018 – 2028 (1 of 2) 175 |
| Figure 6-2: Neurological Procedures by Type, U S , 2018 – 2028 (2 of 2) 176 |
| Figure 6-3: Cerebrospinal Fluid Shunting Procedures, U S , 2018 – 2028 179 |
| Figure 6-4: Interventional treatment of Saccular Aneurysm Procedures by Modality, U S , 2018 – 2028 181 |
| Figure 6-5: Liquid Embolization of AVM Procedures, U S , 2018 – 2028 182 |
| Figure 6-6: Thrombus Management Procedures by Modality, U S , 2018 – 2028 184 |
| Figure 6-7: Neuromodulation Implantation Procedures, U S , 2018 – 2028 (1 of 2) 186 |
| Figure 6-8: Neuromodulation Implantation Procedures, U S , 2018 – 2028 (2 of 2) 187 |
| Figure 6-9: Spinal Cord Stimulation Implantation Procedures, U S , 2018 – 2028 188 |
| Figure 6-10: Deep Brain Stimulation Implantation Procedures, U S , 2018 – 2028 189 |
| Figure 6-11: Intrathecal Pump Procedures, U S , 2018 – 2028 191 |
| Figure 6-12: Stereotactic Surgery Procedures, U S , 2018 – 2028 192 |
| Figure 6-13: Ultrasonic Aspiration Procedures, U S , 2018 – 2028 193 |
| Figure 7-1: Cerebrospinal Fluid Management Market by Segment, U S , 2018 – 2028 (US$M) 197 |
| Figure 7-2: Cerebrospinal Fluid Shunt Market by Segment, U S , 2018 – 2028 200 |
| Figure 7-3: Total Cerebrospinal Fluid Shunt Market, U S , 2018 – 2028 201 |
| Figure 7-4: Adjustable Pressure Cerebrospinal Fluid Shunt Market, U S , 2018 – 2028 203 |
| Figure 7-5: Fixed Pressure Cerebrospinal Fluid Shunt Market, U S , 2018 – 2028 205 |
| Figure 7-6: Cerebrospinal Fluid External Drainage System Market by Segment, U S , 2018 – 2028 206 |
| Figure 7-7: Total Cerebrospinal Fluid External Drainage System Market, U S , 2018 – 2028 207 |
| Figure 7-8: Ventricular Drainage System Market, U S , 2018 – 2028 209 |
| Figure 7-9: Lumbar and Ventricular Drainage System Market, U S , 2018 – 2028 210 |
| Figure 7-10: Leading Competitors, Cerebrospinal Fluid Management Market, U S , 2021 217 |
| Figure 8-1: Detachable Coil Market by Segment, U S , 2018 – 2028 (US$M) 221 |
| Figure 8-2: Total Detachable Coil Market, U S , 2018 – 2028 223 |
| Figure 8-3: Bare Platinum Detachable Coil Market, U S , 2018 – 2028 224 |
| Figure 8-4: Coated Detachable Coil Market, U S , 2018 – 2028 225 |
| Figure 8-5: Leading Competitors, Detachable Coil Market, U S , 2021 231 |
| Figure 9-1: Liquid Embolic Market, U S , 2018 – 2028 234 |
| Figure 9-2: Leading Competitors, Liquid Embolic Market, U S , 2021 239 |
| Figure 10-1: Neurovascular Catheter Market by Segment, U S , 2018 – 2028 244 |
| Figure 10-2: Over-the-Wire Microcatheter Market, U S , 2018 – 2028 247 |
| Figure 10-3: Flow-Directed Microcatheter Market, U S , 2018 – 2028 249 |
| Figure 10-4: Neurovascular Guiding Catheter Market, U S , 2018 – 2028 251 |
| Figure 10-5: Leading Competitors, Neurovascular Catheter Market, U S , 2021 256 |
| Figure 11-1: Neurovascular Guidewire Market, U S , 2018 – 2028 260 |
| Figure 11-2: Leading Competitors, Neurovascular Guidewire Market, U S , 2021 266 |
| Figure 12-1: Neurovascular Stent Market by Segment, U S , 2018 – 2028 (US$M) 270 |
| Figure 12-2: Traditional Neurovascular Stent Market, U S , 2018 – 2028 272 |
| Figure 12-3: Flow Diversion Stent Market, U S , 2018 – 2028 273 |
| Figure 12-4: Intrasaccular Stent Market, U S , 2018 – 2028 275 |
| Figure 12-5: Leading Competitors, Neurovascular Stent Market, U S , 2021 281 |
| Figure 13-1: Balloon Occlusion Device Market, U S , 2018 – 2028 284 |
| Figure 13-2: Leading Competitors, Balloon Occlusion Device Market, U S , 2021 289 |
| Figure 14-1: Total Aneurysm Clip Market, U S , 2018 – 2028 294 |
| Figure 14-2: Aneurysm Clip Market by Indication, U S , 2018 – 2028 (US$M) 295 |
| Figure 14-3: Temporary Aneurysm Clip Market, U S , 2018 – 2028 296 |
| Figure 14-4: Permanent Aneurysm Clip Market, U S , 2018 – 2028 297 |
| Figure 14-5: Aneurysm Clip Market by Material, U S , 2018 – 2028 (US$M) 298 |
| Figure 14-6: Titanium Aneurysm Clip Market, U S , 2018 – 2028 299 |
| Figure 14-7: Cobalt Alloy Aneurysm Clip Market, U S , 2018 – 2028 300 |
| Figure 14-8: Leading Competitors, Aneurysm Clip Market, U S , 2021 304 |
| Figure 14-9: Leading Competitors, Aneurysm Clip Market by Indication, U S , 2021 305 |
| Figure 14-10: Leading Competitors, Aneurysm Clip Market by Material, U S , 2021 305 |
| Figure 15-1: Neurovascular Thrombus Management Market by Segment, U S , 2018 – 2028 310 |
| Figure 15-2: Stent Retriever Market, U S , 2018 – 2028 312 |
| Figure 15-3: Aspiration Catheter Market, U S , 2018 – 2028 313 |
| Figure 15-4: Leading Competitors, Neurovascular Thrombus Management Market, U S , 2021 318 |
| Figure 16-1: Neuromodulation Device by Segment, U S , 2018 – 2028 (US$M) 327 |
| Figure 16-2: Spinal Cord Stimulation Market by Segment, U S , 2018 – 2028 (US$M) 330 |
| Figure 16-3: Total Spinal Cord Stimulation Market, U S , 2018 – 2028 331 |
| Figure 16-4: Spinal Cord Stimulation Generator Market by Battery Type, U S , 2018 – 2028 (US$M) 333 |
| Figure 16-5: Rechargeable Spinal Cord Stimulation Generator Market, U S , 2018 – 2028 334 |
| Figure 16-6: Non-Rechargeable Spinal Cord Stimulation Generator Market, U S , 2018 – 2028 335 |
| Figure 16-7: Spinal Cord Stimulation Generator Market by Channel Type, U S , 2018 – 2028 (US$M) 337 |
| Figure 16-8: Dual-Channel Spinal Cord Stimulation Generator Market, U S , 2018 – 2028 338 |
| Figure 16-9: Tri & Quad-Channel Spinal Cord Stimulation Generator Market, U S , 2018 – 2028 339 |
| Figure 16-10: Spinal Cord Stimulation Lead Market, U S , 2018 – 2028 341 |
| Figure 16-11: Percutaneous Lead Market, U S , 2018 – 2028 342 |
| Figure 16-12: Paddle and Surgical Lead Market, U S , 2018 – 2028 343 |
| Figure 16-13: Spinal Cord Stimulation Implants by Application, U S , 2021 344 |
| Figure 16-14: Deep Brain Stimulation Market, U S , 2018 – 2028 345 |
| Figure 16-15: Total Sacral Nerve Stimulation Market, U S , 2018 – 2028 346 |
| Figure 16-16: Sacral Nerve Stimulation Generator Market by Battery Type, U S , 2018 – 2028 (US$M) 348 |
| Figure 16-17: Rechargeable Sacral Nerve Stimulation Generator Market, U S , 2018 – 2028 349 |
| Figure 16-18: Non-Rechargeable Sacral Nerve Stimulation Generator Market, U S , 2018 – 2028 350 |
| Figure 16-19: Vagus Nerve Stimulation Market, U S , 2018 – 2028 352 |
| Figure 16-20: Gastric Electric Stimulation Market, U S , 2018 – 2028 353 |
| Figure 16-21: Dorsal Root Ganglion Stimulation Market, U S , 2018 – 2028 354 |
| Figure 16-22: Responsive Neurostimulation Device Market, U S , 2018 – 2028 355 |
| Figure 16-23: Leading Competitors, Neuromodulation Device Market, U S , 2021 370 |
| Figure 17-1: Intrathecal Pump Market, U S , 2018 – 2028 375 |
| Figure 17-2: Leading Competitors, Intrathecal Pump Market, U S , 2021 380 |
| Figure 18-1: Stereotactic Device Market by Segment, U S , 2018 – 2028 385 |
| Figure 18-2: Frame-Based Stereotactic Device Market, U S , 2018 – 2028 387 |
| Figure 18-3: Frameless Stereotactic Device Market, U S , 2018 – 2028 388 |
| Figure 18-4: Installed Base, Frame-Based Stereotactic Device Market, U S , 2018 – 2028 389 |
| Figure 18-5: Installed Base, Frameless Stereotactic Device Market, U S , 2018 – 2028 390 |
| Figure 18-6: Leading Competitors, Stereotactic Device Market, U S , 2021 397 |
| Figure 19-1: Neuroendoscopy Market by Segment, U S , 2018 – 2028 402 |
| Figure 19-2: Rigid Endoscope Market, U S , 2018 – 2028 404 |
| Figure 19-3: Flexible Endoscope Market, U S , 2018 – 2028 405 |
| Figure 19-4: Videoscope Market, U S , 2018 – 2028 406 |
| Figure 19-5: Single-Use Endoscope Market, U S , 2018 – 2028 407 |
| Figure 19-6: Neuroendoscopic Hand Instrument Market, U S , 2018 – 2028 408 |
| Figure 19-7: Neuroendoscopy Disposables Market, U S , 2018 – 2028 409 |
| Figure 19-8: Leading Competitors, Neuroendoscopy Market, U S , 2019 415 |
| Figure 20-1: Ultrasonic Aspirator Market by Segment, U S , 2018 – 2028 418 |
| Figure 20-2: Capital Equipment Market, U S , 2018 – 2028 420 |
| Figure 20-3: Installed Base, Ultrasonic Aspirator Market, U S , 2018 – 2028 421 |
| Figure 20-4: Leading Competitors, Ultrasonic Aspirator Market, U S , 2021 427 |
