A Comprehensive Look at the MIS Interbody Device Market

Global MIS interbody device market

The landscape of Minimally Invasive Spine (MIS) surgeries has seen significant advancements, with interbody devices playing a crucial role in enhancing patient outcomes. These devices are segmented into minimally invasive posterior lumbar interbody fusion (MIPLIF), minimally invasive transforaminal lumbar interbody fusion (MITLIF), lateral lumbar interbody fusion (LLIF) and oblique lateral interbody (OLIF) categories, each contributing uniquely to the evolving field. In this blog post, we delve into the market dynamics, growth trends, and regional disparities that define the MIS interbody device market.

Leading the Pack: LLIF 

In the intricate world of MIS interbody devices, LLIF emerged as the frontrunner in 2021, commanding the largest portion of the market value. Projections indicate that LLIF will sustain its dominance with a steady low-single-digit growth rate. This underscores the enduring appeal and efficacy of LLIF procedures, positioning it as a key player over the forecast period.

MITLIF’s Ascension

Securing the second-largest share in the MIS interbody device market in 2021, MITLIF is poised for expansion. Forecasts predict a noteworthy increase in market share, driven by a mid-single-digit growth rate. This trajectory reflects the growing acceptance and demand for MITLIF procedures, positioning it as a significant contender in the evolving landscape.

OLIF: Recovery and Maturation

OLIF, the newest segment in the minimally invasive interbody device market, faced a setback in 2020 due to the global pandemic. However, by 2022, it not only recovered but also surpassed pre-pandemic values. Currently holding the third position in market value, OLIF is anticipated to witness continued growth. As the market matures, the pace of OLIF’s expansion may decrease, but its resilience showcases its potential for long-term impact.

MIPLIF’s Decline

In contrast, MIPLIF, the smallest segment in 2021, is expected to experience a further decline in market share. This is attributed to the heightened demand for LLIF and OLIF procedures, leaving MIPLIF in a stagnant position. The shifting preferences within the market highlight the need for adaptability and innovation.

Regional Dynamics: North America Leads, Asia-Pacific on the Rise

North America asserted its dominance as the largest MIS interbody device market in 2021. Projections suggest that this region will maintain its lead throughout the forecast period. Asia-Pacific, holding the second position, is expected to narrow the gap with North America. Meanwhile, Africa emerged as the fastest-growing region in 2021, signaling a potential shift in the global MIS interbody device market landscape. The number of procedures in 2021 was almost equal between the North American and Asian-Pacific markets. North America had a slightly higher number of procedures, which resulted in a higher number of units sold in the market, leaving Asia Pacific in second position for the number of interbody devices sold in 2021. However, Asia-Pacific is expected to catch up and pass North America in terms of number of units sold.


As we navigate the intricate MIS interbody device market, it’s evident that each segment plays a distinct role in shaping the industry’s future. LLIF maintains its stronghold, MITLIF is on the rise, OLIF showcases resilience, and MIPLIF adapts to changing preferences. Regional variations further emphasize the dynamic nature of this field, with North America leading the charge and emerging regions contributing to the market’s evolution. The future promises exciting developments and innovations as the MIS interbody device market continues to redefine spinal surgeries worldwide.

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