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Swiss physicians write in The Lancet that cartilage cells harvested from the noses of 10 adults successfully produced cartilage transplants that were used to help repair their knee joints. Two years have passed since the transplant, the majority of the patients grew new cartilages in their knees; pain was reduced, knee function was improved as well as the overall quality of life.
“We have developed a new, promising approach to the treatment of articular cartilage injuries,” explained lead researcher Ivan Martin, professor of tissue engineering at the University of Basel and University Hospital Basel in Switzerland.
About 2 million people in Europe and the United States are diagnosed with damage to knee joint cartilage every year, caused by injury or accident. Joint or articular cartilage is the layer of smooth tissue at the ends of bones that eases movement, and protects and cushions the surfaces of the joint where the bones meet. As this tissue has no blood supply, if it gets damaged it cannot regenerate. Eventually, as the cartilage wears away, the bones become exposed and inflamed from rubbing against each other, leading to painful joint conditions like osteoarthritis.
“Our findings confirm the safety and feasibility of cartilage grafts engineered from nasal cells to repair damaged knee cartilage. But use of this procedure in everyday clinical practice is still a long way off as it requires rigorous assessment of efficacy in larger groups of patients and the development of manufacturing strategies to ensure cost effectiveness,” says professor Martin.
For this procedure to become standard, a larger number of patients will have to react positively to the mechanical stress of the knee joint. The nose cartilage extracted for this treatment has a diameter similar to a pencil eraser. The tissue is broken town with enzymes and grown on a porous membrane to stimulate formation.
“Moreover, in order to extend the potential use of this technique to older people or those with degenerative cartilage pathologies like osteoarthritis, a lot more fundamental and pre-clinical research work needs to be done,” Martin adds.
For Further Information
More on the cartilage repair market in Europe can be found in a report suite published by iData Research entitled the European Market for Orthopedic Soft Tissue Repair and Sports Medicine. The suite covers reports on the following markets: ACL/PCL reconstruction, ACL/PCL fixation devices, cartilage repair, meniscal repair, rotator cuff repair, shoulder labrum repair, rotator cuff graft repair, and hip arthroscopy.
Reports provide a comprehensive analysis including units sold, procedure numbers, market value, forecasts, as well as detailed competitive market shares and analysis of major players’ success strategies in each market and segment. To find out more about cartilage repair market data or procedure data, register online or email us at [email protected] for a European Market for Orthopedic Soft Tissue Repair and Sports Medicine brochure and synopsis.
About iData Research
iData Research (www.idataresearch.com) is an international market research and consulting group focused on providing market intelligence for medical device and pharmaceutical companies. iData covers research in: Dental Operatory Equipment, X-Ray Imaging, Vascular Access, Peripheral Vascular, Endoscopy, Interventional Cardiology, Cardiac Surgery, Cardiac Rhythm Management, Electrophysiology, Diagnostic Imaging, Operating Room Equipment, Surgical Microscopes, Robotics and Surgical Navigation, Oncology, Ultrasound, Laparoscopy, Urology, Gynecology, Spinal Implants and VCF, Spinal MIS, Orthopedic Soft Tissue Repair and Regeneration, Orthopedic Trauma, Large and Small Joints, Anesthesiology, Wound Management, Orthopedics, Ophthalmics and more.
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